Effects of oregano (<i>Origanum vulgare</i>) tea on the biochemical profile of Wistar rats <br><b>[Abstract in English]</b>

  • Daniel Pereira Coqueiro Unimar- Universidade de Marília
  • Patricia Cincotto dos Santos Bueno Unimar- Universidade De Marília
  • Elen Landragf Guiguer Unimar - Universidade de Marília
  • Sandra Maria Barbalho Unimar-Universidade de Marília
  • Maricelma da Silva Soares Souza Unimar -Universidade de Marília
  • Adriano Cressoni Araújo Unimar-Universidade de Marília
  • Cleber da Silveira Torres Unimar-Universidade de Marília
  • Gustavo Scacco Unimar-Universidade de Marília
  • Ana Maria Tiveron Unimar-Univesidade de Marília
  • Juliana Machado Costa Unimar-Universidade de Marília
  • Layra Abib Vanzo Unimar-Universidade de Marília
  • Leandro de Oliveira Silva Unimar-Universidade de Marília
  • Murilo Salani Gil Unimar-Universidade de Marília
  • Murilo Delboni Abib Unimar-Universidade de Marília
  • Paulo Brito Reis Rossi Unimar-Universidade de Marília
  • Rafael Fontes Ozi Unimar-Universidade de Marília
  • Thays Delboni Abib Unimar-Universidade de Marília
  • Ulisses Moraes Gonçalves Unimar-Universidade de Marília
Keywords: Origanum Vulgare, Oregano Plant, Blood Glucose, Rats, Models, Animal.

Abstract

AIMS: To evaluate the effects of oregano tea (infusion) on biochemical profile and body weight of Wistar rats. METHODS: Twenty male Wistar rats were divided into two groups of 10 animals each: a treated group, which for 30 days received an infusion of oregano (oregano tea) as the only fluid intake, and a control group, which during the same period received pure water. All animals had free access to the same kind of chow and the liquid (water or oregano tea) was offered ad libitum. The rats were weighed weekly, and their body weights were recorded at 1st, 8th, 15th, 23rd, and 30th days. On day 30, the animals were anesthetized and euthanized with sodium pentobarbital. Blood samples were collected in order to determine total cholesterol, HDL-cholesterol, triglycerides, blood glucose, C-reactive protein, creatinine, aspartate aminotransferase and alanine aminotransferase. RESULTS: The animals that received the infusion of oregano had a lower blood glucose (135.20 ± 22.09) when compared to the control group (152.00 ± 16:51) (p less than 0.05). There were no significant changes in total cholesterol, triglyceride and HDL-cholesterol or in weight gain and the rate of weight gain. CONCLUSIONS: The study of the effects of oregano tea in rats suggests that this plant might have beneficial effects on blood glucose control. It is proposed that further clinical studies are carried out with different concentrations and time periods.

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Author Biographies

Daniel Pereira Coqueiro, Unimar- Universidade de Marília
Centro de Experimentação em Modelos Animais
Patricia Cincotto dos Santos Bueno, Unimar- Universidade De Marília
Coordenadora do Centro de Experimentação em Modelos Animais; Docente do Curso de Medicina da Universidade de Marília.
Published
2012-12-21
How to Cite
Coqueiro, D. P., Bueno, P. C. dos S., Guiguer, E. L., Barbalho, S. M., Souza, M. da S. S., Araújo, A. C., Torres, C. da S., Scacco, G., Tiveron, A. M., Costa, J. M., Vanzo, L. A., Silva, L. de O., Gil, M. S., Abib, M. D., Rossi, P. B. R., Ozi, R. F., Abib, T. D., & Gonçalves, U. M. (2012). Effects of oregano (<i>Origanum vulgare</i>) tea on the biochemical profile of Wistar rats <br><b>[Abstract in English]</b>. Scientia Medica, 22(4), 191-196. Retrieved from https://revistaseletronicas.pucrs.br/ojs/index.php/scientiamedica/article/view/11494
Section
Original Articles