Inadequate food intake in elderly: drug-nutrient interaction

Keywords: malnutrition, aging, polypharmacy, deficiency diseases


Aims: to evaluate the inadequacy of food consumption and the estimated nutrient depletion caused by the use of drugs in the elderly.

Methods: a cross-sectional population study, attended by 427 elderly. Food consumption was obtained from the 24-hour Food Recall Survey and the Research Dietetic History. The use of drugs was assessed by a pharmacotherapeutic questionnaire.

Results: 85.8% of elderly use medications, the most prevalent inhibitors angiotensin converting enzyme inhibitor (29.2%), acetylsalicylic acid (28.7%), hydrochlorothiazide (24.4%), hydroxymethyl-glutaryl coenzyme A reductase enzyme inhibitor (17.0%), calcium carbonate (12.6%) and proton pump inhibitors (8.2%). Acetylsalicylic acid, hydrochlorothiazide and proton pump inhibitors are the drugs that possibly deplete the greatest number of nutrients. Users of hydroxymethyl-glutaryl coenzyme A reductase enzyme inhibitor, 97% could had inadequate for vitamin E; of potassium-sparing diuretics, 90.0% of inadequacy for magnesium; digoxin, 83.3% of inadequate for magnesium and 58.3% for calcium and potassium.

Conclusions: the drugs most commonly used by elderly are responsible for the depletion of numerous micronutrients, often associated with a high prevalence of inadequate consumption, which may cause possible nutritional deficiencies.


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Author Biographies

Carina Duarte Venturini, Hospital de Aeronáutica de Canoas (HACO), Canoas, RS.
Nutricionista. Doutora em Gerontologia Biomédica. Hospital de Aeronáutica de Canoas.
Paula Engroff, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS.
Farmacêutica. Doutora em Gerontologia Biomédica. Pontifícia Universidade Católica Do Rio Grande do Sul.
Vanessa Sgnaolin, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS.
Farmacêutica. Doutora em Gerontologia Biomédica. Pontifícia Universidade Católica Do Rio Grande do Sul.
Raquel Milani El Kik, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS.
Nutricionista. Doutora em Gerontologia Biomédica. Pontifícia Universidade Católica do Rio Grande do Su
Fernanda Bueno Morrone, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS.
Farmacêutica. Doutorado em Ciências Biológicas Bioquímica. Pontifícia Universidade Católica do Rio Grande do Sul.
Irenio Gomes, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS.
Médico. Doutor em Gerontologia Biomédica. Pontifícia Universidade Católica do Rio Grande do Sul.


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How to Cite
Duarte Venturini, C., Engroff, P., Sgnaolin, V., Milani El Kik, R., Bueno Morrone, F., & Gomes, I. (2020). Inadequate food intake in elderly: drug-nutrient interaction. PAJAR - Pan American Journal of Aging Research, 8(1), e34072.
Original Article