Importance and clinical aspects of propolis contact dermatitis

Authors

DOI:

https://doi.org/10.15448/1980-6108.2023.1.44434

Keywords:

Propolis, Contact dermatitis, Patch test, Allergy

Abstract

Aims: propolis is the resinous substance that bees collect from plants to build their hives. The aim of this review was to highlight the importance of diagnosing propolis-related contact dermatitis and relevant clinical aspects of this disease. Methods: narrative literature review carried out by searching the National Library of Medicine (PubMed) and Scientific Electronic Library Online (SciELO) databases. Results: a total of 246 articles were found and, after the selection and reading process, 32 publications were included. Conclusions: delayed-type hypersensitivity to propolis is extremely important because the prevalence of this allergy is increasing in various parts of the world. We need national studies to assess our reality. Proof of the high prevalence in our country will allow this substance to be included in other patch tests series in our country.

Downloads

Download data is not yet available.

Author Biographies

Paulo Eduardo Silva Belluco, Higher School of Health Sciences (ESCS), Brasília, DF, Brazil.

Master in Health Sciences from the Escola Superior de Ciências da Saúde (ESCS), in Brasília, DF, Brazil; doctor from the University of Brasília (UnB), in Brasília, DF, Brazil. Professor of allergy and immunology at the postgraduate course at Faculdade Afya Educação Médica in Brasília, DF, Brazil.

Maurício Domingues Ferreira, Faculty of Medicine, University of São Paulo, SP, SP, Brazil.

PhD in Pathology from the Faculty of Medicine of the University of São Paulo (USP), in São Paulo, SP, Brazil; doctor from the Faculty of Medicine of Jundiaí, in Jundiaí, SP, Brazil. Professor and coordinator of the postgraduate course in allergy and immunology at Faculdade Afya Educação Médica in São Paulo, SP, Brazil.

Fabíola da Silva Maciel Azevedo da Silva Maciel Azevedo, Brasília Air Force Hospital, Brasília, DF, Brazil.

Specialist in Pediatric Allergy and Immunology by the Brazilian Association of Allergy and Immunology (ASBAI). Doctor from the Federal University of Amazonas (UFAM), AM, Brazil. Assistant physician at the Brasília Air Force Hospital, in Brasília, DF, Brazil.

Rosana Zabulon Feijó Belluco, Higher School of Health Sciences (ESCS), Brasília, DF, Brazil.

Doctor from the Federal University of Paraíba (UFPB), in Campina Grande, PB, Brazil. Master's student in Health Sciences at the Higher School of Health Sciences (ESCS), in Brasília, DF, Brazil. Professor at the Faculty of Medicine of the Higher School of Health Sciences (ESCS), Brasília, DF, Brazil.

Carmelia Matos Santiago Reis, Higher School of Health Sciences (ESCS), Brasília, DF, Brazil.

PhD in Dermatology from the Federal University of Rio de Janeiro (UFRJ), in Rio de Janeiro, RJ, Brazil; medical degree from the Federal University of Bahia (UFBA), in Salvador, BA, Brazil Professor and coordinator of postgraduate and extension courses at the Escola Superior de Ciências da Saúde (ESCS), Brasília, DF, Brazil.

References

Walgrave SE, Warshaw EM, Glesne LA. Allergic contact dermatitis from propolis. Dermat (formerly Am J Contact Dermatitis). 2005;16(04):209. http://journals.bcdecker.com/CrossRef/showText.aspx?path=AJD/volume16%2C2005/issue04%2CDecember/ajd_2005_05019/ajd_2005_05019.xml. DOI: https://doi.org/10.2310/6620.2005.05019

Rajpara S, Wilkinson MS, King CM, Gawkrodger DJ, English JSC, Statham BN, et al. The importance of propolis in patch testing-a multicentre survey. Contact Dermatitis. 2009;61(5):287-90. https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0536.2009.01629.x. DOI: https://doi.org/10.1111/j.1600-0536.2009.01629.x

Wilkinson M, Gallo R, Goossens A, Johansen JD, Rustemeyer T, Sánchez-Pérez J, et al. A proposal to create an extension to the european baseline series. Contact Dermatitis. 2018;78(2):101-8. https://onlinelibrary.wiley.com/doi/10.1111/cod.12918. DOI: https://doi.org/10.1111/cod.12918

Wilkinson M, Gonçalo M, Aerts O, Badulici S, Bennike NH, Bruynzeel D, et al. The european baseline series and recommended additions: 2019. Contact Dermatitis. 2019;80(1):1-4. https://onlinelibrary.wiley.com/doi/10.1111/cod.13155. DOI: https://doi.org/10.1111/cod.13155

Belluco PES, Milhomem OS, Belluco JEF, Azevedo F da SM, Belluco RZF, Noves MRCG, et al. O que a bateria padrão latino-americana de teste de contato acrescenta. In: de Carvalho Jr. FF, org. Alergia e Imunologia: abordagens clínicas e prevenções Guarujá-SP: Editora Científica Digital; 2022. p. 50-64. (vol. 2). http://www.editoracientifica.com.br/articles/code/220107212. DOI: https://doi.org/10.37885/220107212

de Groot AC. Propolis: a review of properties, applications, chemical composition, contact allergy, and other adverse effects. Dermat contact, atopic, Occup drug. 2013;24(6):263-82. https://journals.lww.com/01206501-201311000-00002. DOI: https://doi.org/10.1097/DER.0000000000000011

Nyman G, Wagner S, Prystupa-Chalkidis K, Ryberg K, Hagvall L. Contact allergy in western sweden to propolis of four different origins. Acta Derm Venereol. 2020;100(16):adv00256. https://medicaljournalssweden.se/actadv/article/view/1780. DOI: https://doi.org/10.2340/00015555-3615

Funari CS, Ferro VO. Análise de própolis. Ciência e Tecnol Aliment. 2006;26(1):171-8. http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612006000100028&lng=pt&nrm=iso&tlng=pt. DOI: https://doi.org/10.1590/S0101-20612006000100028

da Silva Frozza CO, Garcia CSC, Gambato G, de Souza MDO, Salvador M, Moura S, et al. Chemical characterization, antioxidant and cytotoxic activities of Brazilian red propolis. Food Chem Toxicol. 2013;52:137- 42. http://dx.doi.org/10.1016/j.fct.2012.11.013 DOI: https://doi.org/10.1016/j.fct.2012.11.013

Hasan T, Rantanen T, Alanko K, Harvima RJ, Jolanki R, Kalimo K, et al. Patch test reactions to cosmetic allergens in 1995-1997 and 2000-2002 in Finland – a multicentre study. Contact Dermatitis. 2005;53(1):40-5. https://onlinelibrary.wiley.com/doi/10.1111/j.0105-1873.2005.00630.x. DOI: https://doi.org/10.1111/j.0105-1873.2005.00630.x

Hausen BM. Evaluation of the main contact allergens in propolis (1995 to 2005). Dermatitis. 2005;16(3):127-9. http://journals.lww.com/01206501-200509000-00007. DOI: https://doi.org/10.1097/01206501-200509000-00007

Uter W, Wilkinson SM, Aerts O, Bauer A, Borrego L, Brans R, et al. Patch test results with the european baseline series, 2019/20-joint european results of the ESSCA and the EBS working groups of the ESCD, and the GEIDAC. Contact Dermatitis. 2022;87(4):343-55. https://onlinelibrary.wiley.com/doi/10.1111/cod.14170. DOI: https://doi.org/10.1111/cod.14170

DeKoven JG, Silverberg JI, Warshaw EM, Atwater AR, Reeder MJ, Sasseville D, et al. North American Contact Dermatitis Group Patch Test Results: 2017– 2018. Dermatitis. 2021;32(2):111-23. https://journals.lww.com/10.1097/DER.0000000000000729. DOI: https://doi.org/10.1097/DER.0000000000000729

Nyman GSA, Giménez‐Arnau AM, Grigaitiene J, Malinauskiene L, Paulsen E, Hagvall L. Patch testing with propolis of different geographical origins in a baseline series. Acta Derm Venereol. 2021;101(11):adv00591. https://medicaljournalssweden.se/actadv/article/view/423. DOI: https://doi.org/10.2340/actadv.v101.423

Shi Y, Nedorost S, Scheman L, Scheman A. propolis, colophony, and fragrance cross-reactivity and allergic contact dermatitis. Dermat contact, atopic, Occup drug. 2016;27(3):123-6. https://journals.lww.com/01206501-201605000-00007. DOI: https://doi.org/10.1097/DER.0000000000000186

Gulbahar O, Ozturk G, Erdem N, Kazandi AC, Kokuludag A. Psoriasiform contact dermatitis due to propolis in a beekeeper. Ann Allergy, Asthma Immunol. 2005;94(4):509-11. http://dx.doi.org/10.1016/S1081-1206(10)61123-4. DOI: https://doi.org/10.1016/S1081-1206(10)61123-4

Basista K. Direct and airborne contact dermatitis in a beekeeper from the Małopolska region. Int J Occup Med Environ Health. 2012;25(4):499-500. http://ijomeh.eu/Direct-and-airborne-contact-dermatitis-in-abeekeeper-from-the-malopolska-region,2242,0,2.html. DOI: https://doi.org/10.2478/s13382-012-0054-2

Münstedt K, Hellner M, Hackethal A, Winter D, Von Georgi R. Contact allergy to propolis in beekeepers. Allergol Immunopathol (Madr). 2007;35(3):95-100. http://dx.doi.org/10.1157/13106776. DOI: https://doi.org/10.1157/13106776

Münstedt K, Kalder M. Contact allergy to propolis in beekeepers. Allergol Immunopathol (Madr). 2009;37(6):298-301. https://linkinghub.elsevier.com/retrieve/pii/S0301054609000603 DOI: https://doi.org/10.1016/j.aller.2009.04.005

Langan SM, English JS. Occupational contact dermatitis from propolis in a dental technician. Contact Dermatitis. 2007;56(1):43-43. https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0536.2007.00965.x. DOI: https://doi.org/10.1111/j.1600-0536.2007.00965.x

Lee SX, Boontaveeyuwat E, Thaiwat S, Rustin M, McFadden J. Severe allergic contact dermatitis mimicking angioedema caused by propolis used as a traditional remedy. Contact Dermatitis. 2018;79(3):185-6. https://onlinelibrary.wiley.com/doi/10.1111/cod.13021. DOI: https://doi.org/10.1111/cod.13021

Nyman G, Hagvall L. A case of allergic contact cheilitis caused by propolis and honey. Contact Dermatitis. 2016;74(3):186-7. https://onlinelibrary.wiley.com/doi/10.1111/cod.12500. DOI: https://doi.org/10.1111/cod.12500

Besner Morin C, Alipour Tehrany Y, Sasseville D. Severe allergic contact blepharitis from propolis. Contact Dermatitis. 2020;82(6):399-400. https://onlinelibrary.wiley.com/doi/10.1111/cod.13484. DOI: https://doi.org/10.1111/cod.13484

Navarro‐Triviño FJ, Ruiz‐Villaverde R. Allergic contact dermatitis of head and neck by propolis contained in a shampoo. Contact Dermatitis. 2020;82(6):409-10. https://onlinelibrary.wiley.com/doi/10.1111/cod.13491. DOI: https://doi.org/10.1111/cod.13491

Jacob SE, Chimento S, Castanedo-Tardan MP. Allergic contact dermatitis to propolis and carnauba wax from lip balm and chewable vitamins in a child. Contact Dermatitis. 2008;58(4):242-3. https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0536.2007.1261.x. DOI: https://doi.org/10.1111/j.1600-0536.2007.1261.x

Jensen CD, Andersen KE. Allergic contact dermatitis from cera alba (purified propolis) in a lip balm and candy. Contact Dermatitis. 2006;55(5):312-3. https://onlinelibrary.wiley.com/doi/10.1111/j.1600-0536.2006.00801.x. DOI: https://doi.org/10.1111/j.1600-0536.2006.00801.x

Zhang W, Yan Z. Allergic contact stomatitis caused by propolis throat candies. Contact Dermatitis. 2020;83(1):58-9. https://onlinelibrary.wiley.com/doi/10.1111/cod.13525. DOI: https://doi.org/10.1111/cod.13525

Martínez Pallás I, Conejero Del Mazo C, Prieto Torres L. Allergic contact stomatitis caused by propolis candies. Contact Dermatitis. 2018;78(6):418-9. https://onlinelibrary.wiley.com/doi/abs/10.1111/cod.12958. DOI: https://doi.org/10.1111/cod.12958

Belluco PES, Belluco RZF, Reis CMS. Allergic contact cheilitis caused by propolis: case report. Einstein (São Paulo). 2022;20:eRC6151. https://journal.einstein.br/article/allergic-contact-cheilitis-caused-by-propoliscase-report. DOI: https://doi.org/10.31744/einstein_journal/2022RC6151

Ramien ML, Pratt MD. fixed drug eruption to ingested propolis. Dermatitis. 2012;23(4):173-5. https://journals.lww.com/01206501-201207000-00008. DOI: https://doi.org/10.1097/DER.0b013e318262cac2

Cho E, Lee JD, Cho SH. Systemic Contact Dermatitis from Propolis Ingestion. Ann Dermatol. 2011;23(1):85. https://anndermatol.org/DOIx.php?id=10.5021/ad.2011.23.1.85. DOI: https://doi.org/10.5021/ad.2011.23.1.85

Freedman J, Griggs J, De Padova MP, Tosti A. What’s the “buzz” about propolis? Propolis-induced systemic contact dermatitis. Contact Dermatitis. 2019;80(1):65-7. https://onlinelibrary.wiley.com/doi/10.1111/cod.13131. DOI: https://doi.org/10.1111/cod.13131

Downloads

Published

2023-12-12

How to Cite

Silva Belluco, P. E., Domingues Ferreira, M., da Silva Maciel Azevedo, F. da S. M. A., Zabulon Feijó Belluco, R., & Matos Santiago Reis, C. (2023). Importance and clinical aspects of propolis contact dermatitis. Scientia Medica, 33(1), e44434. https://doi.org/10.15448/1980-6108.2023.1.44434

Issue

Vol. 33 No. 1 (2023): Single Volume - Continuous Flow of Publication

Section

Review Articles

License

Copyright (c) 2023 Scientia Medica

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.