Impact of obesity in morbity and mortality of patients submitted to myocardial revascularization surgery <b>[Abstract in English]</b>
Keywords:
cirurgia de revascularização do miocárdio, obesidade, mediastiniteAbstract
Aims: To evaluate if obesity increase the incidence of post-operative complications and mortality after myocardial revascularization surgery. Methods: Hystorical cohort of 2.445 patients who underwent isolated coronary artery bypass grafting surgery between January 1996 and December 2006 at Hospital São Lucas da PUCRS. The pre-operative variables were: age, sex, functional class of angina (Canadian Heart Association), functional class of heart failure, diabetes, prior cerebral vascular accident (stroke), hypertension, renal dysfunction, chronic obstructive pulmonary disease, smoking, use of Intra-aortic Ballon, use of betablocker, and left ventricular ejection fraction. In the intraoperative, the cardiopulmonary bypass time was evaluated. The postoperative variables included: death, mediastinitis, stroke, respiratory infection, mechanical ventilation time, sepsis, vasoactive drugs, systemic inflammatory response syndrome, myocardial infarction, pulmonary embolism, acute renal disfunction, atrial fibrillation, hypertension, bleeding and lenght of hospital stay. The analysis was performed with statistical software SPSS 10.5, using the Student t test for continuous variables and x square test for categorical variables. Univariate and multivariate analysis were made and the odds ratio (OR) calculated with a 95% confidence interval (CI) and a 0.05 level of significance Results: From the total of 2.445 patients, 11.5% were obese and 56.2% were males. Diabetes, diabetes insulindependent and hypertension were more prevalent in the obese group. There were no differences in relation to death between the two groups: (10.7% in the obese x 8.6% in the non-obese) p = 0.14. In the multivariate analysis obesity was associated with mediastinitis OR=2.7 (95% CI 1.6-4.5), systemic inflammatory response syndrome OR= 2.7 (95% CI 1.8-3.8 ) and pulmonary embolism OR= 2.3 (95% CI 1.3-4.2) Conclusions: In this study obesity increased the risk of the following post-operative complications of myocardial revascularization surgery: mediastinitis, pulmonary embolism an systemic inflammatory response syndrome. There was not a statistically significant increase in mortality. KEY WORDS: MYOCARDIAL REVASCULARIZATION/ mortality; CORONARY ARTERY BYPASS/mortality; CORONARY ARTERY DISEASE/surgery; POSTOPERATIVE PERIOD; OBESITY/complications; MEDIASTINITIS; PULMONARY EMBOLISM; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME.Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright
The submission of originals to Scientia Medica implies the transfer by the authors of the right for publication. Authors retain copyright and grant the journal right of first publication. If the authors wish to include the same data into another publication, they must cite Scientia Medica as the site of original publication.
Creative Commons License
Except where otherwise specified, material published in this journal is licensed under a Creative Commons Attribution 4.0 International license, which allows unrestricted use, distribution and reproduction in any medium, provided the original publication is correctly cited.