Pacientes em hemodiálise: estado inflamatório e massa magra corporal

Autores

  • Annerose Barros PUCRS
  • Alex Oliboni Sussela PUCRS
  • Raisa Felix PUCRS
  • Luiza Silveira Lucas PUCRS
  • Domingos O. d’Avila PUCRS

DOI:

https://doi.org/10.15448/1980-6108.2014.1.14812

Palavras-chave:

DOENÇA RENAL CRÔNICA, HEMODIÁLISE, INFLAMAÇÃO, COMPOSIÇÃO CORPORAL.

Resumo

OBJETIVOS: Investigar a relação do estado inflamatório com a massa magra corporal de pacientes em hemodiálise. MÉTODOS: Um estudo transversal observacional incluiu pacientes em hemodiálise há pelo menos três meses. A análise da composição corporal foi realizada por bioimpedância segmentar multi-frequência (InBody 520®). O estado nutricional associado à inflamação foi avaliado usando o instrumento que computa o Escore Desnutrição-Inflamação. RESULTADOS: A amostra incluiu 59 indivíduos, sendo 30 mulheres. A idade média foi de 58,7±14,4 anos, a mediana do tempo em hemodiálise foi de 24 (9-49) meses, a média do peso seco estimado foi 67,0±14,7 kg e a média de massa magra foi 29,7± 5,5 kg. A mediana do nível sérico de proteína C-reativa ultrassensível foi 8,6 (3,9-18,0) mg/L e acima do limite normal (igual ou menor que 5,0 mg/L), sugerindo a presença de inflamação. O escore desnutrição-inflamação teve mediana de 4 (2-6). Houve correlação significativa entre o escore desnutrição-inflamação e a idade (rs = 0,350, p menor do que 0,01) e com o tempo em diálise: (rs = 0,320, p menor do que 0,05). Inflamação avaliada pelo nível de proteína C-reativa ultrassensível foi significativamente associada à massa magra (rs = - 0,283, p menor do que 0,05). CONCLUSÕES: O aumento do tempo em hemodiálise e a idade aumentada estiveram associados com pior estado nutricional. Nesta população, aparentemente quanto menor a massa magra corporal maior o nível de proteína C-reativa ultrassensível, sugerindo uma possível associação entre a inflamação e a massa magra corporal nestes pacientes.

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Publicado

2014-05-10

Como Citar

Barros, A., Sussela, A. O., Felix, R., Lucas, L. S., & d’Avila, D. O. (2014). Pacientes em hemodiálise: estado inflamatório e massa magra corporal. Scientia Medica, 24(1), 6–10. https://doi.org/10.15448/1980-6108.2014.1.14812

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