Oxidative stress as an emergent cardiometabolic risk factor <b>[Abstract in English]</b>

Authors

  • Maria Gabriela Gottlieb PUCRS
  • Ivana Beatrice Mânica da Cruz UFSM
  • Carla Helena Schwanke PUCRS
  • Luiz Carlos Bodanese PUCRS

Keywords:

OXIDATIVE STRESS, FREE RADICALS, RISK FACTORS, CARDIOVASCULAR DISEASES, METABOLIC DISEASES, METABOLIC SYNDROME X.

Abstract

AIMS: The aim of this article is to review the main aspects of the association of oxidative stress with metabolic syndrome and related diagnostic factors. SOURCE OF DATA: Scientific original and review articles from the MedLine/Pubmed and LILACS databases. SUMMARY OF FINDINGS: Several lines of evidence suggest an association between oxidative stress and medical conditions such as cardiovascular disease, diabetes mellitus, cancer, respiratory diseases and neurological disorders. It has also been postulated that oxidative stress influences the manifestation of metabolic syndrome, characterized by changes in the metabolism of carbohydrates, lipids and proteins, including pro-coagulant and inflammatory effects. CONCLUSIONS: The association of oxidative stress with adiposity and insulin resistance suggests its influence on the appearance of metabolic syndrome. Sedentary lifestyle and poor dietary habits seem to contribute to the increase in oxidative stress and consequent risk of developing cardiovascular disease.

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Author Biographies

Maria Gabriela Gottlieb, PUCRS

Bióloga, doutora em Ciência da Saúde. Instituto de Geriatria e Gerontologia da Pontifícia Universidade Católica do Rio Grande do Sul

Ivana Beatrice Mânica da Cruz, UFSM

Bióloga, doutora em Genética e Biologia Molecular. Departamento de Morfologia Centro de Ciências da Saúde. Universidade Federal de Santa Maria.

Carla Helena Schwanke, PUCRS

Médica geriatra, doutora em Gerontologia Biomédica. Instituto de Geriatria e Gerontologia da Pontifícia Universidade Católica do Rio Grande do Sul. Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul.

Luiz Carlos Bodanese, PUCRS

Médico cardiologista, doutor em Cardiologia. Faculdade de Medicina da Pontifícia Universidade Católica do Rio Grande do Sul. Serviço de Cardiologia do Hospital São Lucas da Pontifícia Universidade Católica do Rio Grande do Sul.

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Published

2010-10-19

How to Cite

Gottlieb, M. G., da Cruz, I. B. M., Schwanke, C. H., & Bodanese, L. C. (2010). Oxidative stress as an emergent cardiometabolic risk factor <b>[Abstract in English]</b>. Scientia Medica, 20(3), 243–249. Retrieved from https://revistaseletronicas.pucrs.br/index.php/scientiamedica/article/view/6270

Issue

Vol. 20 No. 3 (2010)

Section

Review Articles

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