Neonatal abstinence from cocaine, a case report

Authors

DOI:

https://doi.org/10.15448/1980-6108.2022.1.42602

Keywords:

neonatal abstinence syndrome, cocaína, pediatrics

Abstract

Objective: describing a case of an infant exposed to cocaine through breast milk and its clinical repercussions.
Case report: infant, one month and three days old, weighing 3,920g, came to the emergency room due to hypoactivity, sensory impairment and nose bleeding. Afebrile, irritated, tearful, no signs of ventilatory effort or active bleeding. Tests showed leukocytosis 13490/uL, mild metabolic acidosis, increased serum glutamic-oxaloacetic transaminase and enlarged coagulation tests. Other laboratory tests were normal. Toxicological screening revealed cocaine in the infant’s plasma. Toxicological Information Center, recommended monitorization, and clinical support. The patient was discharged from the intensive care unit to the ward five days after admission, with sensorium improvement and a follow-up with specialized teams.
Conclusions: prompt recognition of the neonatal abstinence syndrome allows for better management of it and high chances of recovery for patients. The differential diagnosis with septic condition can be of great importance in conditions like this one.

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Author Biographies

Eduardo Beck Paglioli Neto, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Escola de Medicina, Porto Alegre, RS, Brasil.

Acadêmico da Escola de Medicina da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), em Porto Alegre, RS, Brasil.

Vinícius Castro Pilger, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Escola de Medicina, Porto Alegre, RS, Brasil.

Acadêmico da Escola de Medicina da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), em Porto Alegre, RS, Brasil. 

Lucca Pizzato Tondo, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Escola de Medicina, Porto Alegre, RS, Brasil.

Acadêmico da Escola de Medicina da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), em Porto Alegre, RS, Brasil. 

Mônica Basso Zanotto, Hospital da Criança Santo Antônio, Porto Alegre, RS, Brasil.

Médica intensivista pediátrica do Hospital Santo Antônio, em Porto Alegre, RS, Brasil.

Mateus Sfoggia Giongo, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Escola de Medicina, Porto Alegre, RS, Brasil.

Médico pediatra, e rotineiro do Hospital da Restinga em Porto Alegre, RS. Professor da Escola de Medicina da Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), em Porto Alegre, RS, Brasil. 

References

Villarreal M, Belmonte V, Olivares JL, Abdala A. Trayectorias sanitarias de mujeres consumidoras de cocaína y/o cannabis durante el embarazo. Estudio de cohorte retrospectivo en La Pampa, Argentina. Rev Fac Cien Med Univ Nac Cordoba. 2020;77(2):79-85. https://doi.org/10.31053/1853.0605.v77.n2.26838

D’Avila FB, Limberger RP, Fröehlich PE. Cocaine and crack cocaine abuse by pregnant or lactating mothers and analysis of its biomarkers in meconium and breast milk by LC–MS—A review. Clinical Biochemistry. 2016;49(13-14):1096-103. https://doi.org/10.1016/j.clinbiochem.2016.01.019

Acioli Neto ML, Santos MFS. Os Usos de Crack em um Contexto de Vulnerabilidade: Representações e Práticas Sociais entre Usuários. Psic: Teor e Pesq. 2016;32(3):e32326. https://doi.org/10.1590/0102-3772e32326

Santos JF, Cavalcante CMB, Barbosa FT, Gitaí DLG, Duzzioni M, Tilelli CQ, et al. Maternal, fetal and neonatal consequences associated with the use of crack cocaine during the gestational period: a systematic review and meta-analysis. Arch Gynecol Obstet. 2018;298(3):487- 503. https://doi.org/10.1007/s00404-018-4833-2.

Madruga CS, Laranjeira R, Caetano R, Pinsky I, Zaleski M, Ferri CP. Use of licit and illicit substances among adolescents in Brazil — A national survey. Addictive Behaviors. 2012;37:1171-5. http://dx.doi.org/10.1016/j.addbeh.2012.05.008

Falsaperla R, Zaami S, Aguglia MG, Romano C, Suppiej A, Memo L. Neurophysiological monitoring in neonatal abstinence syndrome from cocaine. Ann Ist Super Sanita. 2020;56(3):390-6. https://doi.org/10.4415/ann_20_03_18.

Kocherlakota P. Neonatal abstinence syndrome. Pediatrics. 2014;134(2):e547-61. https://doi.org/10.1542/peds.2013-3524

Bauer CR, Langer JC, Shankaran S, Bada HS, Lester B, Wright LL, et al. Acute neonatal effects of cocaine exposure during pregnancy. Arch Pediatr Adolesc Med. 2005;159(9):824-34. https://doi.org/10.1001/archpedi.159.9.824.

Lamy S, Laqueille X, Thibaut F. [Consequences of tobacco, cocaine and cannabis consumption during pregnancy on the pregnancy itself, on the newborn and on child development: A review]. Encephale. 2015;41(Suppl 1):S13–20. https://doi.org/10.1016/j.encep.2014.08.012

Hudak ML, Tan RC, Committee on Drugs, Committee on Fetus and Newborn, American Academy of Pediatrics. Neonatal drug withdrawal. Pediatrics. 2012;129(2):e540-60. https://doi.org/10.1542/peds.2011-3212.

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Published

2022-09-22

How to Cite

Neto, E. B. P., Pilger, V. C., Tondo, L. P., Zanotto, M. B., & Giongo, M. S. (2022). Neonatal abstinence from cocaine, a case report. Scientia Medica, 32(1), e42602. https://doi.org/10.15448/1980-6108.2022.1.42602

Issue

Vol. 32 No. 1 (2022): Single Volume

Section

Case Reports

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