Applicability and safety of sodium nitroprusside to control arterial pressure during thrombolysis in the treatment of acute ischemic stroke <b>[Abstract in English]</b>

Authors

  • Fábio Pascotto de Oliveira Hospital São Lucas
  • Charles Luiz Klant Hospital São Lucas
  • Mauricio André Gheller Friedrich Hospital São Lucas Pucrs

Keywords:

acidente vascular cerebral, alteplase, nitroprussiato, isquêmico, pressão arterial

Abstract

Aims: To report the experience with sodium nitroprusside in the treatment of acute ischemic cerebral stroke. Methods: A retrospective study, conducted by review of hospital charts, included patients who suffered an acute ischemic cerebral stroke and received thrombolytic therapy with alteplase, from May 2005 to July 2007. Results: Of 48 patients who meet the inclusion criteria, 15 received sodium nitroprusside to control the arterial pressure. One patient (6,7%) died, and none had symptomatic intracerebral hemorrhage. The median score for National Institute of Health Stroke Scale at the arrival was 10, and at discharge was 2,8. Conclusions: Sodium nitroprusside in the acute ischemic cerebral stroke was applicable and safe. Larger and prospective studies are necessary to corroborate these results and evaluate its potential protective properties. KEY WORDS: NITROPRUSSIDE; STROKE; ACUTEPHASE REACTION; TISSUE PLASMINOGEN ACTIVATOR; BLOOD PRESSURE; BRAIN ISCHEMIA.

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Author Biographies

Fábio Pascotto de Oliveira, Hospital São Lucas

neurologia

Charles Luiz Klant, Hospital São Lucas

Departamento de neurologia

Mauricio André Gheller Friedrich, Hospital São Lucas Pucrs

Departamento neurologia, área de neurovascular

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Published

2008-08-09

How to Cite

Oliveira, F. P. de, Klant, C. L., & Friedrich, M. A. G. (2008). Applicability and safety of sodium nitroprusside to control arterial pressure during thrombolysis in the treatment of acute ischemic stroke <b>[Abstract in English]</b>. Scientia Medica, 18(3), 119–123. Retrieved from https://revistaseletronicas.pucrs.br/index.php/scientiamedica/article/view/2098

Issue

Vol. 18 No. 3 (2008)

Section

Original Articles

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