Fatores prognósticos e sobrevida a longo prazo em carcinoma espinocelular bucal

Um estudo transversal

Autores

DOI:

https://doi.org/10.15448/1980-6108.2021.1.41124

Palavras-chave:

prognóstico, análise de sobrevida, registros médicos, neoplasias bucais, carcinoma de células escamosas

Resumo

Objetivo: este estudo objetivou avaliar a sobrevida a longo prazo e fatores prognósticos de pacientes com carcinoma espinocelular bucal em uma região pouco desenvolvida economicamente do Brasil.
Métodos: os dados foram obtidos a partir da análise de registros médicos de 210 pacientes com carcinoma espinocelular bucal tratados em um hospital especializado em oncologia que presta serviços ao Sistema Único de Saúde em um estado do Nordeste brasileiro entre janeiro de 2006 e dezembro de 2008. Informações clínicas, sociodemográficas e referentes aos tratamentos realizados, recidivas e evoluções foram coletadas. As curvas de sobrevida foram estimadas pelo método de Kaplan-Meier, sendo utilizado o teste de Log-rank para comparar as curvas.
Resultados: a sobrevida média no estudo foi de 47.4 meses (95% IC = 38.2 - 56.7). As taxas de sobrevida global em 5 e 10 anos foram de 29% e 19.8%, respectivamente. Indivíduos com idade superior a 60 anos (RR = 1.70; 95% IC = 1.06 - 2.73), que apresentaram metástases regionais (RR = 2.51; 95% IC = 1.55 - 4.08), recidivas tumorais (RR = 3.18; 95% IC = 1.88 - 5.39) e que foram tratados apenas não cirurgicamente (RR = 2.10; 95% IC = 1.31 - 3.35) tiveram pior prognóstico.
Conclusões: idade avançada, presença de metástases regionais, recidivas tumorais e tratamento apenas não cirúrgico foram preditores de pior sobrevida em pacientes diagnosticados com carcinoma espinocelular bucal.

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Biografia do Autor

Carlos Eduardo Moura Carvalho Rocha, Universidade Estadual do Piauí (UESPI), Teresina, PI, Brazil.

Medical student at State University of Piauí (UESPI), Teresina, PI, Brazil.

Júlio César Saraiva Santos, Universidade Estadual do Piauí (UESPI), Teresina, PI, Brazil.

Medical doctor at State University of Piauí (UESPI), Teresina, PI, Brazil.

Rafael Everton Assunção Ribeiro da Costa, Universidade Estadual do Piauí (UESPI), Teresina, PI, Brazil.

Medical student at State University of Piauí (UESPI), Teresina, PI, Brazil.

Eduardo Salmito Soares Pinto, Secretaria de Saúde do Estado do Piauí (Sesapi), Teresina, PI, Brazil.

Resident doctor at Getúlio Vargas Hospital, Teresina, PI, Brazil.

Ana Luisa Rios Barbosa de Almeida, Hospital São Marcos (HSM), Teresina, PI, Brazil; Associação Piauiense de Combate ao Câncer Alcenor Almeida, Teresina, PI, Brazil.

Specialization in Buco-Maxillo-Facial Surgery and Traumatology; specialization in Stomatology; coordinator of the Dental Service in São Marcos Hospital, Teresina, PI, Brazil.

Cacilda Castelo Branco Lima, Universidade Federal do Piauí (UFPI), Teresina, PI, Brazil.

PhD in Dentistry from the University of Minas Gerais (UFMG), Belo Horizonte, MG, Brazil; Professor at the Federal University of Piauí (UFPI), Teresina, PI, Brazil.

Luciana Tolstenko Nogueira, Universidade Estadual do Piauí (UESPI), Teresina, PI, Brazil.

PhD in Dental Clinics from the Faculty of Dentistry São Leopoldo Mandic (SLMANDIC), Campinas, SP, Brazil; Professor at State University of Piauí (UESPI), Teresina, PI, Brazil.

Lucielma Salmito Soares Pinto, Universidade Estadual do Piauí (UESPI), Teresina, PI, Brazil.

PhD in Stomatopathology from the University of Campinas (Unicamp), Campinas, SP, Brazil; Professor at State University of Piauí (UESPI), Teresina, PI, Brazil.

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Publicado

2021-10-29

Como Citar

Rocha, C. E. M. C., Santos, J. C. S., Costa, R. E. A. R. da, Pinto, E. S. S., Almeida, A. L. R. B. de, Lima, C. C. B., … Pinto, L. S. S. (2021). Fatores prognósticos e sobrevida a longo prazo em carcinoma espinocelular bucal: Um estudo transversal. Scientia Medica, 31(1), e41124. https://doi.org/10.15448/1980-6108.2021.1.41124

Edição

v. 31 n. 1 (2021): Volume Único

Seção

Artigo de Pesquisa

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Copyright (c) 2021 Scientia Medica

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Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.