Las mujeres posmenopáusicas con concentraciones elevadas de TNF-α presentaron menor reducción de grasas

Un ensayo clínico controlado aleatorizado

Autores/as

DOI:

https://doi.org/10.15448/2357-9641.2022.1.42759

Palabras clave:

pérdida de peso, inflamación, dieta rica en proteínas, acondicionamento físico humano

Resumen

Objetivos: evaluar los efectos de una dieta rica en proteínas asociadas al ejercicio físico sobre marcadores de inflamación y composición corporal. 
Métodos: el estudio es un ensayo clínico de 12 semanas con 26 mujeres posmenopáusicas que recibieron un plan de alimentación alto en proteínas individualizado y participaron en tres sesiones de entrenamiento físico cada semana. La ingesta de alimentos se controló a través de ocho recordatorios de alimentos de 24 horas y se estimó la ingesta habitual de alimentos. Al inicio y al final del estudio se midieron variables antropométricas; el contenido de grasa y la masa magra se estimaron mediante fórmulas, y se recolectó sangre para la cuantificación de proteína C reactiva (PCR), incluidos TNF-α, IL-6, IL-10 e IL-18. Se realizó ANOVA one-way. 
Resultados: se identificó que 13 participantes tenían una dieta alta en proteínas (HP) y 13 tenían una dieta estándar en proteínas (SP). El grupo HP perdió peso (p=0,032); sin embargo, no hubo cambios en el contenido de grasa, el contenido de masa magra o los marcadores inflamatorios. Solo las mujeres que iniciaron el programa con valores más bajos de TNF-α mostraron una pérdida significativa de grasa total (p=0,049), grasa visceral (p=0,037), triglicéridos (p=0,031) y colesterol LDL (p=0,003). 
Conclusiones: las mujeres posmenopáusicas con altas concentraciones de marcadores inflamatorios responden menos a las estrategias de modificación de la composición corporal. 

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Biografía del autor/a

Jamylle Araújo Almeida, Universidade Federal de Sergipe, São Cristóvão, SE, Brasil.

Mestre em Ciências da Nutrição e graduada em Nutrição pela Universidade Federal de Sergipe (UFS), em São Cristóvão, SE, Brasil. 

Liliane Viana Pires, Universidade Federal de Sergipe, São Cristóvão, SE, Brasil.

Mestre em Ciências da Nutrição e graduada em Nutrição pela Universidade Federal de Sergipe (UFS), em São Cristóvão, SE, Brasil.

Luana Edla Lima, Universidade Federal de Sergipe, São Cristóvão, SE, Brasil.

Mestre em Ciências da Nutrição e graduada em Nutrição pela Universidade Federal de Sergipe (UFS), em São Cristóvão, SE, Brasil.

Francismayne Batista Santana, Universidade Federal de Sergipe, São Cristóvão, SE, Brasil.

Especialista em Saúde do Adulto e do Idoso e graduada em Nutrição pela Universidade Federal de Sergipe (UFS), em São Cristóvão, SE, Brasil.

Walderi Monteiro da Silva Júnior, Universidade Federal de Sergipe, São Cristóvão, SE, Brasil.

Doutor em Clínica Médica pela Universidade Federal do Rio de Janeiro (UFRJ), no Rio de Janeiro, RJ, Brasil. Mestrado em Engenharia Biomédica e graduado em fisioterapia pela Universidade Federal da Paraíba. Professor Associado da Universidade Federal de Sergipe (UFS), em São Cristóvão, SE, Brasil.

Marzo Edir da Silva Grigoletto, Universidade Federal de Sergipe, São Cristóvão, SE, Brasil.

Doutor em “Ciencias Aplicadas a la Actividad Física y el Deporte” pela Universidad de Córdoba, com pós-doutorado no Hospital Reina Sofia. Professor da Universidade Federal de Sergipe, em São Cristóvão, SE, Brasil.

Raquel Simões Mendes Netto, Universidade Federal de Sergipe, São Cristóvão, SE, Brasil.

Doutora e mestre em Ciências dos Alimentos pela Universidade de São Paulo (USP), em São Paulo, SP, Brasil. Graduada em Nutrição pela Universidade Federal de Pernambuco. Professora associada da Universidade Federal de Sergipe (UFS), em São Cristóvão, SE, Brasil.

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Publicado

2022-06-23

Cómo citar

Almeida, J. A., Pires, L. V., Lima, L. E., Santana, F. B., Júnior, W. M. da S., Grigoletto, M. E. da S., & Netto, R. S. M. (2022). Las mujeres posmenopáusicas con concentraciones elevadas de TNF-α presentaron menor reducción de grasas: Un ensayo clínico controlado aleatorizado. PAJAR - Pan-American Journal of Aging Research, 10(1), e42759. https://doi.org/10.15448/2357-9641.2022.1.42759

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Vol. 10 Núm. 1 (2022): Número único

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