É possivel desprescrever medicamentos agonistas dos receptores benzodiazepínicos em idosos?
DOI:
https://doi.org/10.15448/2357-9641.2023.1.45098Palavras-chave:
desprescrições, receptores de GABA-A, idosoResumo
Objetivo: verificar a viabilidade e os fatores relacionados à desprescrição de agonistas de receptores de benzodiazepínicos (ARBZ).
Métodos: estudo longitudinal, prospectivo e = intervencionista, realizado com idosos atendidos no ambulatório de psiquiatria geriátrica, os quais foram divididos em dois grupos: os usuários e os não usuários de ARBZ. Os instrumentos utilizados foram: Questionário geral, Escala Depressão Geriátrica Reduzida, Inventário de Ansiedade Geriátrica e Índice de Qualidade do Sono de Pittsburg.
Resultados: foram avaliados 74 pacientes, 40 (54,1%) usuários de ARBZ e 34 (45,9%) não usuários, com média de idade de 71,3±7,5 anos. Pacientes em uso de ARBZ apresentaram maior taxa de abandono ao processo de desprescrição 26 (65%). Sete pacientes cessaram o uso de ARBZ completamente (17,5%) e cinco reduziram (12,5%). Em relação aos sintomas depressivos e ansiosos, as médias dos escores foram menores na avaliação final. Em relação à qualidade do sono, os usuários de ARBZ apresentaram valores superiores na linha de base e, ao fim do tratamento, ambos os grupos apresentaram redução desses valores.
Conclusão: a desprescrição é viável e segura. No entanto, existe uma resistência tanto da parte do paciente como dos prescritores. Os níveis de ansiedade, de- pressão e qualidade do sono melhoram após a retirada dos medicamentos ARBZ.
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Copyright (c) 2023 Letícia Güenter Dannebrock, Paula Engroff, Vanessa Sgnaolin, Isabela de Paula Bueno, Alfredo Cataldo Neto

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