Chorioretinal lesions in mothers of children with congenital toxoplasmosis in the National Collaborative Chicago-based, Congenital Toxoplasmosis Study

  • A. Gwendolyn Noble University of Chicago and Children's Memorial Hospital
  • Paul Latkany New York Eye and Ear Hospital, New York University, St. Luke's Roosevelt Hospital Center
  • Jaroslaw Kusmierczyk University of Chicago
  • Marilyn Mets Children's Memorial Hospital, Northwestern University
  • Peter Rabiah
  • Kenneth Boyer Rush University Medical Center
  • Jessica Jalbrzikowski University of Chicago
  • Kristen Wroblewski University of Chicago
  • Theodore Karrison University of Chicago
  • Charles N. Swisher Children's Memorial Hospital
  • William F. Mieler University of Chicago
  • Paul Meier Columbia Univeristy
  • Rima McLeod University of Chicago

Abstract

AIMS: To determine whether mothers of children with congenital toxoplasmosis have chorioretinal lesions consistent with toxoplasmosis. METHODS: Ophthalmologists in our study have examined 173 children with congenital toxoplasmosis in a hospital outpatient setting. These children were referred to us by their primary care physicians. One hundred and thirty mothers of these children had retina examinations of both eyes at least once. Main outcome measure was lesion(s) consistent with ocular toxoplasmosis. RESULTS: Of 130 mothers examined between 1991-2005, 10 (7.7%, 95% Confidence Interval 3.8%, 13.7%) had chorioretinal lesions which likely represent resolved toxoplasmic chorioretinitis. Most of these were small peripheral chorioretinal lesions. None reactivated between 1991-2005. CONCLUSIONS: Chorioretinal lesions consistent with quiescent ocular toxoplasmosis occur in mothers of children with congenital toxoplasmosis in the United States.

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Author Biography

Rima McLeod, University of Chicago
Professor at the University of Chicago in the Department of Surgery, Section of Ophthalmology
Published
2010-02-25
How to Cite
Noble, A. G., Latkany, P., Kusmierczyk, J., Mets, M., Rabiah, P., Boyer, K., Jalbrzikowski, J., Wroblewski, K., Karrison, T., Swisher, C. N., Mieler, W. F., Meier, P., & McLeod, R. (2010). Chorioretinal lesions in mothers of children with congenital toxoplasmosis in the National Collaborative Chicago-based, Congenital Toxoplasmosis Study. Scientia Medica, 20(1), 20-26. https://doi.org/10.15448/1980-6108.2010.1.5930