Antibacterial activity of the crude hydroalcoholic extract of Stryphnodendron adstringens on dental caries microorganisms

Authors

  • Sara Pimenta Soares
  • Luciana Assirati Casemiro
  • Adriana Helena Chicaro Vinholis
  • Marcio Luis Andrade Silva
  • Wilson Roberto Cunha
  • Carlos Henrique Gomes Martins

Keywords:

Antimicrobial activity, “barbatimão”, Stryphnodendron adstringens, oral microorganisms, dental caries

Abstract

Purpose: Stryphnodendron adstringens (“barbatimão”) is a medicinal plant of the Leguminoseae family from the Brazilian “cerrado”. This plant is used in folk medicine because of its healing, anti-inflammatory, antiseptic, and hemostatic effects. The aim of this work was to evaluate the antibacterial activity of the “barbatimão” crude hydroalcoholic extract against cariogenic microorganisms. Methods: The broth dilution method was used to determine the Minimum Inhibitory Concentration (MIC) of the “barbatimão” hydroalcoholic extract against Enterococcus faecalis, Streptococcus salivarius, Streptococcus sanguinis, Streptococcus mitis, Streptococcus mutans, Streptococcus sobrinus, and Lactobacillus casei. Results: The “barbatimão” hydroalcoholic extract showed antibacterial activity against S. mitis e L. casei, with MIC ranging from 350 to >400 μg/mL. Conclusion: These results suggest that the “barbatimão” hydroalcoholic extract might be used as an adjuvant measure to control dental caries. Key words: Antimicrobial activity; “barbatimão”; Stryphnodendron adstringens; oral microorganisms; dental caries

Author Biographies

Sara Pimenta Soares

Graduanda do Curso de Odontologia da UNIFRAN

Luciana Assirati Casemiro

Profa Dra do Curso de Odontologia da UNIFRAN

Adriana Helena Chicaro Vinholis

Profa Dra do Curso de Odontologia da UNIFRAN

Marcio Luis Andrade Silva

Prof Dr do curso de Química da UNIFRAN

Wilson Roberto Cunha

Prof Dr do curso de Química da UNIFRAN

Carlos Henrique Gomes Martins

Prof Dr do curso de Biomedicina da UNIFRAN

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Published

2008-06-22

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Section

Original Article