Collagen composite with silicate and hydroxyapatite as endodontic material: preparation and characterization


  • Miguel Menezes E´Gues
  • Márcio De Paula
  • Gilberto Goissis


Collagen, silicate, hydroxyapatite, Endodontics


Purpose: This study aimed to prepare and characterize a new collagen composite with silicate and hydroxyapatite as a potential endodontic material for pulp capping and pulpotomy. Methods: Anionic type I collagen was mixed with silicate (White Portland cement) and hydroxyapatite in several proportions. The materials were characterized by standard differential scanning calorimetry, thermogravimetry, scanning electron microscopy (SEM), energy dispersion x-ray, and infrared spectrometry. Results: The presence of collagen in the composite was observed by means of typical thermal transitions for collagen type I (∼48ºC), independently from the proportion used. SEM images showed collagen fibers interconnecting silicate particles. The chemical composition of all collagen composites was essentially the same as that of the original silicate. Conclusion: These results showed that the collagen matrix structure of the tested composite was not altered, which is an important feature for a “more natural” tissue repair in Endodontics. Key words: Collagen; silicate; hudroxyapatite; endodontics

Author Biographies

Miguel Menezes E´Gues

Miguel Antônio Menezes E’Gues é dentista na cidade de Campo Grande/MS e mestre em Biogenharia pela Escola de Engenharia de São Carlos da Universidade de São Paulo.

Márcio De Paula

Márcio de Paula é químico, formado pela Universidade de São Paulo (IQSC/USP), doutor em química analítica (ênfase em biomateriais) pelo Instituto de Química de São Carlos (IQSC/USP) e pesquisador de desenvolvimento tecnológico industrial pela Proline Biomédica Ltda.






Original Article