Supplementation with fish oil reduces morphological aspects of muscle damage induced by intense exercise in rats

Autores

  • Daniel Pereira Coqueiro Unimar- Universidade de Marília http://orcid.org/0000-0001-7267-9137
  • Patricia Cincotto dos Santos Bueno Universidade de Marília- Unimar
  • Manuel de Jesus Simões Universidade Federal de São Paulo

DOI:

https://doi.org/10.15448/1980-6108.2018.4.31470

Palavras-chave:

inflamação, exercício, tecido muscular, ácidos graxos poli-insaturados, nutrição.

Resumo

***Suplementação com óleo de peixe reduz aspectos morfológicos de lesão muscular induzida por exercícios intensos em ratos***

OBJETIVOS: Investigar os efeitos do exercício resistido e da ingestão de óleo de peixe na morfologia da fibra muscular em ratos Wistar.

MÉTODOS: Quarenta e oito animais realizaram exercício resistido e foram divididos inicialmente em dois grupos. Um dos grupos não recebia óleo de peixe e o outro grupo ingeria o óleo de peixe. Os animais do segundo grupo realizaram o treinamento e ingeriram o óleo de peixe por um período de oito semanas. Ao final da última sessão de exercício resistido os animais foram organizados em seis subgrupos de oito cada, segundo o intervalo de tempo (12, 24 e 48 horas) transcorrido até o procedimento de retirada do músculo gastrocnêmio. Em cada tempo determinado após a última sessão de exercício resistido, o músculo gastrocnêmio foi retirado para análise morfológica.

RESULTADOS: As células do músculo esquelético dos animais que não receberam óleo de peixe apresentaram escores maiores de edema, especialmente as dos grupos que tiveram os músculos retirados em 24 e 48 horas. No grupo que ingeriu o óleo de peixe observou-se menor quantidade de infiltrado inflamatório e áreas de necrose reduzidas em comparação com os animais que se exercitavam sem o uso de óleo de peixe, em todos os intervalos de tempo pós-exercício.

CONCLUSÕES: A ingestão de óleo de peixe atenuou as alterações morfológicas no tecido muscular após exercícios de alta intensidade.

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Biografia do Autor

Daniel Pereira Coqueiro, Unimar- Universidade de Marília

Centro de Experimentação em Modelos Animais

Patricia Cincotto dos Santos Bueno, Universidade de Marília- Unimar

Department of Biochemistry and Pharmacology

Manuel de Jesus Simões, Universidade Federal de São Paulo

Department of Structural and Functional Biology

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Publicado

2018-10-17

Como Citar

Coqueiro, D. P., Bueno, P. C. dos S., & Simões, M. de J. (2018). Supplementation with fish oil reduces morphological aspects of muscle damage induced by intense exercise in rats. Scientia Medica, 28(4), ID31470. https://doi.org/10.15448/1980-6108.2018.4.31470

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