Historical evolution of the surgical treatment of pancreatic cancer
DOI:
https://doi.org/10.15448/1980-6108.2014.2.17647Keywords:
CANCER OF PANCREAS, PANCREATICODUODENECTOMY, HISTORY OF MEDICINE, SURGERYAbstract
AIMS: To review the main historical aspects of the evolution of the treatment of pancreatic cancer. SOURCE OF DATA: Literature review through PubMed. Selected articles on the history of the treatment of pancreatic cancer were analyzed. SUMMARY OF FINDINGS: Complete surgical resection is the only therapeutic alternative that may allow cure of patients with pancreatic cancer. However, pancreaticoduodenectomy is one of the most challenging surgical procedures, requiring surgeons with a high level of training for its secure implementation. Several protagonists were involved in the evolution of the surgical technique in pancreatic surgery until the procedure reached current levels of security. CONCLUSIONS: Despite the safety with which pancreaticoduodenectomy is currently performed, postoperative survival in pancreatic cancer is still insufficient, suggesting that technical issues are just one of the steps needed to improve outcome. Better screening methods to diagnose earlier tumors, identification of high risk patients and improvement in adjuvant treatment are needed to increase the cure rate of this neoplasm.Downloads
References
REFERÊNCIAS
Hariharan D, Saied A, Kocher HM. Analysis of mortality rates for pancreatic cancer across the world. HPB (Oxford). 2008;10:58-62.
Siegel R, Ward E, Brawley O, Jemal A. Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin. 2011;61(4):212-36.
Bassi C, Malleo G. The unsolved mystery of Johann Georg Wirsung and of (his?) pancreatic duct. Surgery. 2011;149(1):153-5.
Carter R. Assassination of Johann Georg Wirsung (1589-1643): mysterious medical murder in Renaissance Padua. World J Surg. 1998;
:324-6.
Busnardo AC, DiDio LJ, Tidrick RT, Thomford NR. History of the pancreas. Am J Surg. 1983;146(5):539-50.
McClusky III DA, Skandalakis LJ, Colborn GL, Skandalakis JE. Harbinger or Hermit? Pancreatic Anatomy and Surgery through the Ages -Part 2. World J. Surg. 2002;26:1370-1381.
Praderi RC. History of pancreatic surgery. In: Trede M, Carter DC, ed., Surgery of the Pancreas, New York, Churchill Livingstone,1993.
Schnelldorfer T, Adams DB, Warshaw AL, Lillemoe KD, Sarr MG. Forgotten pioneers of pancreatic surgery. Ann Surg. 2008;247:191–202.
Howard JM. History of pancreatic head resection—the evaluation of surgical technique. Am J Surg. (Suppl Oct 2007);194:S6–S10.
Schnelldorfer T, Sarr MG. Alessandro Codivilla and the First Pancreatoduodenectomy. Arch Surg. 2009;144(12):1179-84.
Halsted WS. Contributions to the surgery of the bile passages, especially of the common bile-duct. Boston Med Surg J. 1899;141:645.
Souza HP, Alves JM, Toneto MG, Gabiatti G, Pandolfo G. Papiloduodenectomia como Alternativa Terapêutica para Tumores Papilares. Rev Col Brasil Cir. 1998; 25(6):423-6.
Are C, Dhir M, Ravipati L. History of pancreaticoduodenectomy: early misconceptions, initial milestones and the pioneers. HPB (Oxford). 2011;13(6):377-84.
Brunschwig A. Resection of head of pancreas and duodenum for carcinoma—pancreatoduodenectomy. Surg Gynecol Obstet. 1937;65:681-684.
Chen TS, Chen PS. The Whipples and their legacies in medicine. Surg Gynecol Obstet. 1993;176: 501-6.
Whipple AO. A reminiscence: pancreaticoduodenectomy. Surgery. 1963;20:221-5.
Whipple AO, Parsons WB, Mullins CR. Treatment of carcinoma of the ampulla of Vater. Ann Surg. 1935;102:763-9.
Peters JH, Carey LC. Historical review of pancreatoduodenectomy. Am J Surg. 1991;161:219-25.
Whipple AO. Reminiscence. Rev Surg. 1963;20:221–5.
Whipple AO. Pancreaticoduodenectomy for islet carcinoma. Ann Surg. 1945;121:847–52.
Rockey EW.Total pancreatectomy for carcinoma:case report. Ann Surg. 1943;118(4):603-11.
Priestley JT, Comfort MW, Radcliffe J. Total pancreatectomy for hyperinsulinism due to an islet-cell adenoma: survival and cure at sixteen months after operation presentation of metabolic studies. Ann Surg. 1944;119(2):211-21.
Pliam MB, ReMine WH. Further evaluation of total pancreatectomy. Arch Surg. 1975;110:506–12.
Sarr MG, Behrns KE, van Heerden JA. Total pancreatectomy. An objective analysis of its use in pancreatic cancer. Hepato- Gastroenterology. 1993;40:418–21.
Sohn TA, Yeo CJ, Cameron JL, Hruban RH, Fukushima N, Campbell KA, Lillemoe KD. Intraductal papillary mucinous neoplasms of the pancreas: An updated experience. Ann Surg. 2004;239,788-797.
Müller MW, Friess H, Kleeff J, Dahmen R, Wagner M, Hinz U, Breisch-Girbig D, Ceyhan GO, Büchler MW. Is there still a role for total pancreatectomy? Ann Surg. 2007;246:966-974.
Fortner JG. Regional resection of cancer of the pancreas: a new surgical approach. Surgery. 1973;73:307-320.
Fortner JG. Regional pancreatectomy for cancer of the pancreas, ampulla, and other related sites. Tumor staging and results. Ann Surg. 1984;
(4):418-25.
Harrison LE, Klimstra DS, Brennan MF. Isolated portal vein involvement in pancreatic adenocarcinoma:a contraindication for resection? Ann Surg.1996;224:342–7.
Crile G Jr. The advantages of bypass operations over radical pancreatoduodenectomy in the treatment of pancreatic carcinoma. Surg Gynecol Obstet 1970;130:1409–53.
Gudjonsson B. Cancer of the pancreas: 50 years of surgery. Cancer 1987; 60:2284-303.
Shapiro TM. Adenocarcinoma of the pancreas: a statistical analysis of biliary bypass vs Whipple resection in good risk patients. Ann Surg. 1975 Dec;182(6):715-21.
Trede M, Schwall G, Saeger HD. Survival after pancreatoduodenectomy. 118 consecutive resections without an operative mortality. Ann Surg. 1990 Apr;211(4):447-58.
Cameron JL, Pitt HA, Yeo CJ, Lillemoe KD, Kaufman HS, Coleman J. One hundred and forty-five consecutive pancreaticoduodenectomies without mortality.Ann Surg. 1993;217:430-435.
Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA, et al. Six hundred fifty consecutive pancreaticoduodenectomiesin the 1990s: pathology, complications, and outcomes. Ann Surg 1997;226:248–57.
Makary MA, Winter JM, Cameron JL, Campbell KA, Chang D, Cunningham SC, Riall TS, Yeo CJ. Pancreaticoduodenectomy in the very elderly. J Gastrointest Surg. 2006 Mar;10(3):347-56.J Gastrointest Surg 2006;10:347–356.
Traverso LW, Longmire WP. Preservation of the pylorus in pancreaticoduodenectomy. Surg Gynecol Obstet 1978;146:959–62.
Traverso LW, Longmire WP. Preservation of the pylorus in pancreaticoduodenectomy— a follow-up evaluation. Ann Surg 1980;192:306–10.
Sohn TA, Yeo CJ, Cameron JL, et al. Resected adenocarcinoma of the pancreas—616 patients: results, outcomes, prognostic indicators. J Gastrointest Surg 2000;4:567–79.
van Heek NT, Kuhlmann KF, Scholten RJ, de Castro SM, Busch OR, van Gulik TM, Obertop H, Gouma DJ. Hospital volume and mortality after pancreatic resection: a systematic review and an evaluation of intervention in the Netherlands. Ann Surg. 2005 Dec;242(6):781-8.
Ohtsuka, T.; Tanaka, M.; Miyazaki, K. Gastrointestinal function and quality of life after pylorus-preserving pancreatoduodenectomy. J. Hepatobiliary Pancreat. Surg. 2006, 13, 218-224.
Fitzsimmons, D.; Johnson, C.D. Quality of life after treatment of pancreatic cancer. Langenbecks Arch Surg. 1998, 383, 145-151.
Huang JJ, Yeo CJ, Sohn TA, Lillemoe KD, Sauter PK, Coleman J, Hruban RH, Cameron JL. Quality of life and outcomes after pancreaticoduodenectomy. Ann Surg. 2000 Jun;231(6):890-8.
Gagner M, Pomp A. Laparoscopic pylorus preserving pancreatoduodenectomy.Surg Endosc. 1994;8(5):408–10.
Kendrick ML, Cusati D. Total laparoscopic pancreaticoduodenectomy: feasibility and outcome in an early experience. Arch Surg.2010;145(1):19–23.
Oettle H, Post S, Neuhaus P, et al. Adjuvant chemotherapy with gemcitabine vs observation in patients undergoing curative-intent resection of pancreatic cancer: a randomized controlled trial. JAMA. Jan 17 2007;
(3):267-77.
Pisters PW, Wolff RA, Janjan NA, Cleary KR, Charnsangavej C, Crane CN. Preoperative paclitaxel and concurrent rapid-fractionation radiation for resectable pancreatic adenocarcinoma: toxicities, histologic response rates, and event-free outcome. J Clin Oncol. May 15 2002; 20(10):2537-44.
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