Functional capacity and inspiratory muscular strength of liver transplant candidates
DOI:
https://doi.org/10.15448/1983-652X.2019.3.34217Keywords:
liver cirrhosis, effort test, respiratory muscles, physiotherapy.Abstract
Objective: To compare functional capacity among cirrhotic, with and without inspiratory muscle weakness, and to correlate functional capacity with respiratory muscle strength.
Materials and Methods: Cross-sectional study conducted in a teaching hospital. Cirrhotic patients under protocol for liver transplantation aged 18 years or older were included. Patients who were contraindicated to perform the six-minute walk test (6MWT) were excluded. Physical therapy evaluation was performed with sociodemographic variables collection, functional capacity analysis through the 6MWT and respiratory muscle strength measurement through manovacuometry to obtain the maximum inspiratory pressure (MIP) and the maximum expiratory pressure (MEP). The patients were divided into two groups: group I - MIP ≤ -80 cmH2O (GI) – respiratory muscle weakness; and group II – MIP > -80 cmH2O (GII) – no respiratory muscle weakness. A significance level of 5% (p<0.05) was considered.
Results: 51 cirrhotic patients were analyzed. There was no significant difference (p=0.19) in the distance covered between GI (449±86.37m) and GII (477.66±69.19m) in the 6MWT. GI showed significantly lower MIP (p<0.0001) and MEP (p=0.02) than GII. GI patients had significantly lower MIP in predicted percentage (p<0.0001) than GII patients (68.9±17% vs 97.8±17.7% respectively). There was a significant correlation (r=0.4 p=0.02) between MIP and 6MWT in both GI and GII.
Conclusion: There was no difference in functional capacity between cirrhotic with and without inspiratory muscle weakness. In spite of the statistical correlation between inspiratory muscle strength and functional capacity in patients with and without inspiratory muscle weakness, the results do not suggest a clinically important correlation between these variables.
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