White blood cell count of patients with oral squamous cell carcinoma at the time of diagnosis: a cross-sectional retrospective study of a population from southern Brazil

Autores

  • Kelem de Antoni Brunischaki DDS
  • Myrian Camara Brew Universidade Luterana do Brasil - ULBRA
  • Caren Serra Bavaresco Universidade Luterana do Brasil - ULBRA
  • Sergio Augusto Quevedo Miguens Jr Universidade Luterana do Brasil - ULBRA

DOI:

https://doi.org/10.15448/1980-6523.2018.1.29190

Palavras-chave:

carcinoma, squamous cell, mouth, white blood cells, inflammation.

Resumo

OBJECTIVE: To describe sociodemographic variables and verify changes in white blood cells of patients with oral squamous cell carcinoma (OSCC).
METHODS: Cross-sectional retrospective study that used secondary data of patients with OSCC, attended at the Oral Medicine Service of the School of Dentistry of ULBRA, between 2010 and 2014.
RESULTS: 87.3% of the population were male, white (71%), age superior to 60 years (38.7%), urban worker (61.3%), without changing in the overall health at query time (67.7%) and residents of the municipality of Canoas/RS (93.6%). The most prevalent injuries sites were the buccal floor, alveolar ridge, corners of the mouth and gums (61.3%). 74.2% of the sample were smokers and 45.2% drinkers. As for the WBC, most patients presented values within the normal range: total leukocytes (77.4%), lymphocytes (87.1%) and neutrophils (96.8%). 
CONCLUSION: The profile of the sample was consistent with literature: white males over the age of 40 years, smokers/former-smokers and alcoholics/ex-alcoholics. The patients did not show changes in the white blood cells (leukogram) values. It is recommended that more research should be conducted in this area of knowledge, due to the importance of the subject.

 

*** Contagem de glóbulos brancos de pacientes com carcinoma espinocelular bucal no momento diagnóstico: estudo transversal retrospectivo de uma população do sul do Brasil ***

OBJETIVO: descrever o perfil sociodemográfico e verificar alterações nas células brancas do sangue de pacientes com Carcinoma Espino Celular Bucal (CECB).
MÉTODOS: estudo transversal retrospectivo que utilizou dados secundários de pacientes com CECB, atendidos no Serviço de Estomatologia do Curso de Odontologia da ULBRA, entre 2010 e 2014.
RESULTADOS: 87,3% da população eram de homens, brancos (71%), com idade superior a 60 anos (38,7%), trabalhadores urbanos (61,3%), sem alteração de saúde geral no momento da consulta (67,7%) e moradores do município de Canoas/RS (93,6%). Os sítios mais prevalentes das lesões foram o assoalho bucal, rebordo alveolar, fundo de sulco, comissura labial e gengiva (61,3%). 74,2% da amostra eram de fumantes e 45,2% eram etilistas. Quanto ao leucograma, a maioria dos pacientes apresentou valores dentro da normalidade de leucócitos totais (77,4%), linfócitos (87,1%) e neutrófilos (96,8%).
CONCLUSÃO: o perfil da amostra foi compatível com o determinado na literatura: homens brancos com idade superior a 40 anos, fumantes/ex-fumantes e etilistas/ex-etilistas. Os pacientes não apresentaram alterações no leucograma, verificado pela contagem das células brancas do sangue. Recomenda-se que mais pesquisas sejam realizadas nesta área do conhecimento, devido à importância do tema.

Palavras-chave: carcinoma de células escamosas; boca; leucócitos; inflamação.

Biografia do Autor

Myrian Camara Brew, Universidade Luterana do Brasil - ULBRA

Professor, School of Dentistry

Caren Serra Bavaresco, Universidade Luterana do Brasil - ULBRA

Professor of Postgraduate Program, School of Dentistry

Sergio Augusto Quevedo Miguens Jr, Universidade Luterana do Brasil - ULBRA

Professor of Postgraduate Program, School of Dentistry

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2018-12-30

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Artigo Original