Comparison between cardiovascular effects of adrenaline and phenylephrine associated with lidocaine and the effects of felypressin with prilocaine during intrabucal anesthesia in ASA I patients

Autores

  • Tatiany Bertollo Cozer Ribeiro da Costa Federal University of Espírito Santo
  • Antônio de Melo Cabral Faesa Odontology College
  • Renata Pittella Cançado Federal University of Espirito Santo http://orcid.org/0000-0002-9997-2744

DOI:

https://doi.org/10.15448/1980-6523.2018.1.29848

Palavras-chave:

felypressin, epinephrine, vasoconstrictors agents, blood pressure, oral surgery.

Resumo

OBJECTIVE: Evaluate the cardiovascular effects by infiltration of 1:100.000 epinephrine and 1:2.500 phenylephrine associated with 2% lidocaine compared with the effects by infiltration of 0.03 IU/ml felypressin with 3% prilocaine, during surgery of third molars in ASA I patients.
METHODS: Eighteen patients were divided into two groups. In group I (GI), the effects of epinephrine vs felypressin were evaluated and in group II (GII), the effects of phenylephrine vs felypressin. Cardiovascular parameters: systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and oxygen saturation (SatO2) were measured in pre, trans and post-operative periods.
RESULTS: Statistical analysis (T-TEST) on the cardiovascular parameters demonstrated with significance that, GI: felypressin presented HR average reduction in the postoperative period and SatO2 average reduction in trans and postoperative periods. For GII: felypressin presented SatO2 average reduction in the postoperative period; SBP averages for patients submitted to phenylephrine increased in trans and postoperative periods; and DBP averages for patients submitted to phenylephrine increased in pre and trans-operative periods.
COCLUSION: We can conclude that phenylephrine may lead to increased SBP and DBP and felypressin generated a reduction in HR and SatO2. All these changes were well tolerated by ASA I patients.

 

*** Comparação entre os efeitos cardiovasculares da adrenalina e fenilefrina associadas à lidocaína e os efeitos da felipressina com a prilocaína durante a anestesia intrabucal em pacientes ASA I ***

OBJETIVO: Avaliar os efeitos cardiovasculares da infiltração de adrenalina 1:100.000 e fenilefrina 1:2.500 associadas à lidocaína a 2% comparados com os efeitos da felipressina 0,03 UI/ml associada à prilocaína a 3% durante a cirurgia de terceiros molares em pacientes ASA I.
MEDOTODOLOGIA: Dezoito voluntários foram divididos em dois grupos. No grupo I (GI), adrenalina vs felipressina e, no grupo II (GII), fenilefrina vs felipressina. Os parâmetros de frequência cardíaca (FC), saturação de oxigênio (SatO2), pressão arterial sistólica (PAS) e pressão arterial diastólica (PAD) foram avaliados nos períodos pré, trans e pós-operatórios.
RESULTADOS: A análise estatística feita através do teste t pareado demonstrou que, no GI, a felipressina apresentou redução na FC no período pós-operatório e redução na SatO2 nos períodos trans e pós-operatórios. No GII, a felipressina apresentou redução de SatO2 no período pós-operatório. As PAS para os pacientes submetidos à fenilefrina apresentaram-se aumentadas nos períodos trans e pós-operatórios e as PAD para os pacientes submetidos à fenilefrina apresentaram-se aumentadas nos períodos pré e trans-operatórios.
CONCLUSÃO: A partir destes resultados podemos concluir que a fenilefrina pode acarretar aumento da PAS e PAD e a felipressina gerou uma redução na FC e SatO2 alterações essas bem toleradas por estes pacientes

Palavras-chave: anestésicos locais; vasoconstritores; parâmetros cardiovasculares.

Biografia do Autor

Renata Pittella Cançado, Federal University of Espirito Santo

Oral and Maxillofacial Surgery

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2018-12-30

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