Human pulp pesponse to Portland cement and MTA

Autores

  • Antônio Vinícius Holanda Barbosa Department of endodontics, School of Dentistry, FACIPE
  • Valdeci Elias dos Santos Junior Universidade de Pernambuco
  • Márcia Marques Martins Department of Restorative Dentistry, School of Dentistry, University of São Paulo (USP)
  • Leila Soares Ferreira Department of Restorative Dentistry, University of Ibirapuera
  • Ana Paula Veras Sobral Department of Oral Pathology, School of Dentistry of Pernambuco, University of Pernambuco

DOI:

https://doi.org/10.15448/1980-6523.2018.1.29259

Palavras-chave:

biocompatibility, human pulp, mineral trioxide aggregate, portland cement, pulp capping.

Resumo

OBJECTIVE: To investigate the pulpal response to direct pulp capping in healthy human teeth with Portland cement (PC) as against mineral trioxide aggregate (MTA) as control.
METHODS: Forty healthy human third molars indicated for extraction were randomly divided into two groups: PC and MTA. The teeth had iatrogenic pulp exposed and direct pulp capping with PC or MTA. After 1, 7, 14 and 21 days, the teeth were extracted and prepared for histological examination and bacterial detection. The Mann-Whitney test was applied for statistical analysis (p < 0.05).
RESULTS: The MTA presented higher capacity to form of dentin bridges at 14- and 21-day intervals (p < 0.05). However, no significant statistical difference was found between the groups at all evaluated intervals (p > 0.05) for the response variables of inflammatory cells, soft tissue organization and bacterial staining.
CONCLUSION: The PC has a biocompatibility equivalent to the MTA but with a lower capacity to form of dentin bridges. Therefore, MTA should be the material of choice for direct pulp capping.

 

*** Resposta da polpa humana ao cemento Portland e ao MTA ***

OBJETIVO: Investigar a resposta pulpar ao capeamento pulpar direto em dentes humanos saudáveis com cimento Portland (PC) em relação ao agregado de trióxido mineral (MTA), como controle.
METODOLOGIA: Foram utilizados 40 molares humanos sadios indicados para extração, aleatoriamente divididos em dois grupos: PC e MTA. Os dentes tiveram a polpa exposta iatrogenicamente e em seguida foi realizado o capeamento pulpar direto com PC ou MTA. Após 1, 7, 14 e 21 dias, os dentes foram extraídos e preparados para exame histológico e detecção bacteriana. O teste de Mann-Whitney foi aplicado para análise estatística (p < 0,05).
RESULTADOS: O MTA apresentou maior capacidade de formação de pontes dentinárias nos intervalos de 14 e 21 dias (p < 0,05). No entanto, não foi encontrada diferença estatística significativa entre os grupos em todos os intervalos avaliados (p > 0,05) para as variáveis de resposta de células inflamatórias, organização de tecidos moles e coloração bacteriana.
CONCLUSÃO: O PC tem uma biocompatibilidade equivalente ao MTA, mas com menor capacidade de formar pontes dentinárias. Portanto, o MTA deve ser o material de escolha para o capeamento direto da polpa.

Palavras-chave: biocompatibilidade; polpa humana; agregado de trióxido mineral; cimento portland; capeamento pulpar.

Referências

Oliveira MG, Xavier CB, Demarco FF, Pinheiro ALB, Costa AT, Pozza DH. Comparative chemical study of MTA and Portland cements. Braz Dent J 2007;18:3-7.

https://doi.org/10.1590/S0103-64402007000100002

Johnson BR. Considerations in the selection of a root-end filling material. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;87:398-404.

https://doi.org/10.1016/S1079-2104(99)70237-4

Lee BN, Son HJ, Noh HJ, Koh JT, Chang HS, Hwang IN, et al. Cytotoxicity of newly developed ortho MTA root-end filling materials. J Endod 2012;38:1627-1630.

https://doi.org/10.1016/j.joen.2012.09.004

Cunha SA, Rached FJ Jr, Alfredo E, León JE, Perez DE. Biocompatibility of sealers used in apical surgery: a histological study in rat subcutaneous tissue. Braz Dent J 2011;22:299-305.

https://doi.org/10.1590/S0103-64402011000400007

Silva GF, Guerreiro-Tanomaru JM, Sasso-Cerri E, Tanomaru-Filho M, Cerri OS. Histological and histomorphometrical evaluation of furcation perforations filled with MTA, CPM and ZOE. Int Endod J 2011;44:100-10.

https://doi.org/10.1111/j.1365-2591.2010.01803.x

Al Hiyasat AS, Al Sa’Eed OR, Darmani H. Quality of cellular attachment to various root-end filling materials. J Appl Oral Sci 2012;20:82-8.

https://doi.org/10.1590/S1678-77572012000100015

Camilleri J. Characterization of hydration products of mineral trioxide aggregate. Int Endod J 2008;41:408-17.

https://doi.org/10.1111/j.1365-2591.2007.01370.x

Natu VP, Dubey N, Loke GCL, et al. Bioactivity, physical and chemical properties of MTA mixed with propylene glycol. Journal of Applied Oral Science 2015;23:405-411.

https://doi.org/10.1590/1678-775720150084

Hugar SM, Deshpande SD. Comparative investigation of clinical/radiographical signs of mineral trioxide aggregate and formocresol on pulpotomized primary molars. Contemporary Clinical Dentistry 2010;1:146-151.

https://doi.org/10.4103/0976-237X.72779

Güven EP, Taşlı PN, Yalvac ME, Sofiev N, Kayahan MB, Sahin F. In vitro comparison of induction capacity and biomineralization ability of mineral trioxide aggregate and a bioceramic root canal sealer. Int Endod J 2013;46:1173-82.

https://doi.org/10.1111/iej.12115

Espir CG, Guerreiro-Tanomaru JM, Spin-Neto R, Chávez-Andrade GM, Berbert FL, Tanomaru-Filho M. Solubility and bacterial sealing ability of MTA and root-end filling materials. J Appl Oral Sci 2016;24:121-5.

https://doi.org/10.1590/1678-775720150437

Scelza MZ, Campos CA, Scelza P, Adeodato CS, Barbosa IB, de Noronha F, Montalli V, Napimoga M, de Araújo VC, Alves GG. Evaluation of Inflammatory Response to Endodontic Sealers in a Bone Defect Animal Model. J Contemp Dent Pract 2016;17:536-41.

Cox CF, Keall CL, Keall HJ, Ostro E, Bergenholtz G. Biocompatibility of surface-sealed dental materials against exposed pulps. J Prosthet Dent 1987;57:1-8.

https://doi.org/10.1016/0022-3913(87)90104-1

Cox CF, Sübay RK, Suzuki S, Suzuki SH, Ostro E. Biocompatibility of various dental materials: pulp healing with a surface seal. Int J Periodontics Restorative Dent 1996;16:240-51.

Akimoto N, Momoi Y, Kohno A, Suzuki S, Otsuki M, Suzuki S, Cox CF. Biocompatibility of Clearfil Liner Bond 2 and Clearfil AP-X system on nonexposed and exposed primate teeth. Quintessence Int 1998;29: 177-88.

Saidon J, He J, Zhu Q, Safavi K, Spångberg LS. Cell and tissue reactions to mineral trioxide aggregate and Portland cement. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003;95:483-9.

https://doi.org/10.1067/moe.2003.20

Menezes R, Bramante CM, Letra A, Carvalho VG, Garcia RB. Histologic evaluation of pulpotomies in dog using two types of mineral trioxide aggregate and regular and white Portland cements as wound dressings. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004;98:376-9.

https://doi.org/10.1016/j.tripleo.2004.03.008

Holland R, de Souza V, Murata SS, Nery MJ, Bernabé PF, Otoboni Filho JA, Dezan Júnior E. Healing process of dog dental pulp after pulpotomy and pulp covering with mineral trioxide aggregate or Portland cement. Braz Dent J 2001;12:109-13.

Camilleri J, Montesin FE, Di Silvio L, Pitt Ford TR. The chemical constitution and biocompatibility of accelerated Portland cement for endodontic use. Int Endod J 2005;38:834-42.

https://doi.org/10.1111/j.1365-2591.2005.01028.x

Sarkar NK, Caicedo R, Ritwik P, Moiseyeva R, Kawashima I. Physicochemical basis of the biologic properties of mineral trioxide aggregate. J Endod 2005;31:97-100.

https://doi.org/10.1097/01.DON.0000133155.04468.41

Gonçalves JL, Viapiana R, Miranda CE, Borges AH, Cruz Filho AM. Evaluation of physico-chemical properties of Portland cements and MTA. Braz Oral Res 2010;24:277-83.

https://doi.org/10.1590/S1806-83242010000300004

Accorinte ML, Loguercio AD, Reis A, Carneiro E, Grande RH, Murata SS, Holland R. Response of human dental pulp capped with MTA and calcium hydroxide powder. Oper Dent 2008;33:488-95.

https://doi.org/10.2341/07-143

Ford TR, Torabinejad M, Abedi HR, Bakland LK, Kariyawasam SP. Using mineral trioxide aggregate as a pulp-capping material. J Am Dent Assoc 1996;127:1491-4.

https://doi.org/10.14219/jada.archive.1996.0058

Takita T, Hayashi M, Takeichi O, Ogiso B, Suzuki N, Otsuka K, Ito K. Effect of mineral trioxide aggregate on proliferation of cultured human dental pulp cells. Int Endod J 2006;39:415-22.

https://doi.org/10.1111/j.1365-2591.2006.01097.x

Faraco IM Jr, Holland R. Response of the pulp of dogs to capping with mineral trioxide aggregate or a calcium hydroxide cement. Dent Traumatol 2001;17:163-6.

https://doi.org/10.1034/j.1600-9657.2001.170405.x

Vivan RR, Zapata RO, Zeferino MA, Bramante CM, Bernardineli N, Garcia RB, et al. Evaluation of the physical and chemical properties of two commercial and three experimental root-end filling materials. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010;110:250-6.

https://doi.org/10.1016/j.tripleo.2010.04.021

Downloads

Publicado

2018-12-30

Edição

Seção

Artigo Original