Congenital syphilis: prevalence and related factors in university hospitals of Pelotas
DOI:
https://doi.org/10.15448/1983-652X.2019.3.33415Keywords:
congenital syphilis, prenatal care, epidemiology.Abstract
Objective: To evaluate the prevalence of congenital syphilis and the factors associated with the disease in neonates from two university hospitals in the city of Pelotas, RS.
Materials and Methods: A cross-sectional, retrospective study whose cases of congenital syphilis were identified through the compulsory notifications of each hospital from January 2016 to December 2017. The characteristics of the neonates with the disease were compared to those of the live births in Pelotas during the study period in these hospitals.
Results: The prevalence of congenital syphilis was 2.4% and the probability of investigation was higher in the offspring of younger, non-white pregnant women with lower educational level. The neonates investigated were 40% more likely to be born with low birth weight.
Conclusion: The prevalence of congenital syphilis remains high and the main impact on the newborn health was the increase in the probability of low birth weight.
References
Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de Vigilância, Prevenção e Controle das Doenças Sexualmente Transmissíveis, Aids e Hepatites Virais. Manual técnico para diagnóstico da sífilis. Brasília: Ministério da Saúde; 2016. https://doi.org/10.26512/2016.02.d.20359
Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Departamento de DST, Aids e Hepatites Virais. Protocolo Clínico e Diretrizes Terapêuticas (PCDT): atenção integral às pessoas com Infecções Sexualmente Transmissíveis (IST). Brasília: Ministério da Saúde; 2015. https://doi.org/10.26512/2016.02.d.20359
Brasil. Ministério da Saúde. Comissão Nacional de Incorporação de Tecnologias no SUS. (CONITEC). Protocolo clínico e diretrizes terapêuticas para prevenção da transmissão vertical de HIV, sífilis e hepatites virais. Brasília: Ministério da Saúde; 2017. https://doi.org/10.11606/t.5.2019.tde-17042019-092843
Brasil. Ministério da Saúde. Secretaria de Atenção à Saúde. Departamento de Ações Programáticas e Estratégicas. Atenção à saúde do recém-nascido: guia para os profissionais de saúde: cuidados gerais. Brasília: Ministério da Saúde; 2011. https://doi.org/10.18554/reas.v5i2.1426
Domingues RM, Leal MC. Incidence of congenital syphilis and factors associated with vertical transmission: data from the Birth in Brazil study. Cad Saúde Pública. 2016;32(6):e00082415. http://dx.doi.org/10.1590/0102-311X00082415
Bowen V, Su J, Torrone E, Kidd S, Weinstock H. Increase in incidence of congenital syphilis - United States, 2012-2014. MMWR Morb Mortal Wkly Rep. 2015;64(44):1241-5. https://doi.org/10.15585/mmwr.mm6444a3
Brasil. Ministério da Saúde. Secretaria de Vigilância em Saúde. Boletim epidemiológico: sífilis 2017;48(36):1-42. https://doi.org/10.7476/9788575416068.0002
Brasil. Ministério da Saúde. Transmissão vertical do HIV e sífilis: estratégias para redução e eliminação. Brasília: Ministério da Saúde; 2014. https://doi.org/10.1590/s0034-89102011000400026
Domingues RMSM, Saracen V, Hartz ZMA, Leal MC. Sífilis congênita: evento sentinela da qualidade da assistência pré-natal. Rev Saúde Pública. 2013;47(1):147-57. http://dx.doi.org/10.1590/S0034-89102013000100019
Yeganeh N, Watts HD, Camarca M, Soares G, Joao E, Pilotto JH, Gray G, Theron G, Santos B, Fonseca R, Kreitchmann R, Pinto J, Mussi-Pinhata M, Ceriotto M, Machado DM, Grinzstein B, Veloso VG, Morgado MG, Bryson Y, Mofenson LM, Nielsen-Saines K; NICHD HPTN 040P1043 Study Team. Syphilis in HIV-infected mothers and infants: results from the NICHD/HPTN 040 study. Pediatr Infect Dis J. 2015;34(3):e52-7. http://dx.doi.org/10.1097/INF.0000000000000578
Acosta LMW, Gonçalves TR, Barcellos NT. Coinfecção HIV/ sífilis na gestação e transmissão vertical do HIV: um estudo a partir de dados da vigilância epidemiológica. Rev Panam Salud Publica. 2016;40(6):435-42. https://doi.org/10.1590/s1020-49892006000300005
Soares LG, Zarpellon B, Soares LG, Baratieri T, Lentsck MH, Mazza VA. Gestational and congenital syphilis: maternal, neonatal characteristics and outcome of cases. Rev Bras Saúde Mater Infant. 2017;17(4):781-9. http://dx.doi.org/10.1590/1806-93042017000400010
Magalhães DMS, Kawaguchi IAL, Dias A, Calderon IMP. Sífilis materna e congênita: ainda um desafio. Cad Saúde Pública. 2013;29(6):1109-20. http://dx.doi.org/10.1590/S0102-311X2013000600008
Campos ALA, Araújo MAL, Melo SP, Gonçalves MLC. Epidemiologia da sífilis gestacional em Fortaleza, Ceará, Brasil: um agravo sem controle. Cad Saúde Pública. 2010;26(9):1747-55. http://dx.doi.org/10.1590/S0102-311X2010000900008
Dou L, Wang X, Wang F, Wang Q, Qiao Y, Su M, Jin X, Qiu J, Song L, Wang A. Epidemic profile of maternal syphilis in China in 2013. BioMed Res Int. 2016;2016:9194805. http://dx.doi.org/10.1155/2016/9194805
Araújo CL, Shimizu HE, Sousa AIA, Hamann EM. Incidência da sífilis congênita no Brasil e sua relação com a Estratégia Saúde da Família. Rev Saúde Pública. 2012;46(3):479-86. http://dx.doi.org/10.1590/S0034-89102012000300010
Brasil. Ministério da Saúde. Portaria n° 570, de 1° junho 2000 [Internet]. Brasília: Ministério da Saúde; 2000 [capturado em 15 out. 2019]. Disponível em: http://bvsms.saude.gov.br/bvs/saudelegis/gm/2000/prt0570_01_06_2000_rep.html. https://doi.org/10.5327/z1679443520190289
Lafetá KR, Martelli Júnior H, Silveira MF, Paranaíba LM. Maternal and congenital syphilis underreported and difficult to control. Rev Bras Epidemiol. 2016;19(1):63-74. http://dx.doi.org/10.1590/1980-5497201600010006
Lima BGC, Costa MCN, Dourado MIC. Avaliação da qualidade do rastreamento de HIV/aids e sífilis na assistência pré-natal. Epidemiol Serv Saúde. 2008;17(2):125-7.
Barros AJ, Santos IS, Victora CG, Albernaz EP, Domingues MR, Timm IK, Matijasevich A, Bertoldi AD, Barros FC. Coorte de nascimentos de Pelotas, 2004: metodologia e descrição. Rev Saúde Pública. 2006;40(3):402-13. http://dx.doi.org/10.1590/S0034-89102006000300007
Muricy CL, Pinto Júnior VL. Congenital and maternal syphilis in the capital of Brazil. Rev Soc Bras Med Trop. 2015;48(2):216-9. http://dx.doi.org/10.1590/0037-8682-0168-2014
Cardoso ARP, Araújo MAL, Cavalcante MS, Frota MA, Melo SP. Análise dos casos de sífilis gestacional e congênita nos anos de 2008 a 2010 em Fortaleza, Ceará, Brasil. Ciênc Saúde Coletiva. 2018;23(2):563-74. http://dx.doi.org/10.1590/1413-81232018232.01772016
Patel SJ, Klinger EJ, O'Toole D, Schillinger JA. Missed opportunities for preventing congenital syphilis infection in New York City. Obstet Gynecol. 2012;120(4):882-8. http://dx.doi.org/10.1097/AOG.0b013e31826ac25f
Taylor MM, Nurse-Findlay S, Zhang X, Hedman L, Kamb ML, Broutet M, Kiarie J. Estimating benzathine penicillin need for the treatment of pregnant women diagnosed with syphilis during antenatal care in high-morbidity countries. PLoS One. 2016;11(7):e0159483. http://dx.doi.org/10.1371/journal.pone.0159483
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