Management of mucous membrane pemphigoid with dapsone plus weekly steroid injections in a young patient: a case report

Authors

  • Gurumoorthy Kaarthikeyan
  • N.D. Jayakumar
  • Ogoti Padmalatha
  • Joseph M. Thachil
  • Sheeja Varghese
  • Thiruvengadam Chandrasekar

Keywords:

Pemphigoid, topical steroids, dapsone, steroid injections, immunofluorescence

Abstract

Purpose: Mucous Membrane Pemphigoid (MMP) is an autoimmune subepithelial blistering disorder usually affecting older individuals. This paper describes the pharmacological management of MMP in a young patient. Case description: A 23 year-old woman showed erythematous ulcerative gingiva in the maxillary palatal region and around the retromolar region. A perilesional excisional biopsy was done, and the histologic and immunohistochemical analysis confirmed the clinical diagnosis of MMP as the cause of desquamative gingivitis in this patient. The patient was treated with topical steroids plus daily Dapsone 100 mg and weekly steroid injections (40 mg). The lesions began to resolve after 12 weeks of therapy. Conclusion: This case of MMP in a young female patient was effectively managed with a combination therapy of topical steroids, Dapsone and steroid injections.

Author Biographies

Gurumoorthy Kaarthikeyan

Senior lecturer, Department of Periodontics, Saveetha dental college&hospitals

N.D. Jayakumar

Professor,Dept. of Periodontics

Ogoti Padmalatha

Professor, dept. of Periodontics

Thiruvengadam Chandrasekar

Professor, dept. of Oral pathology

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Published

2009-11-16

Issue

Section

Case Report