Secretory IgA and salivary flow in smokers and non-smokers
Keywords:
Saliva, immunoglobulin A, secretory, tobacco,Abstract
Objective: To compare the concentration levels of secretory immunoglobulin A (SIgA) and salivary flow between smokers and non-smokers. Methods: The sample was recruited at the Dentistry School of the Pontifical Catholic University of Rio Grande do Sul. The participants were asked to spit into the tubes for five minutes (unstimulated saliva). The tubes containing the samples were immediately weighed to calculate the salivary flow through the gravimetric method. Single radial immunodiffusion plates were used as well as a graduated magnifying glass specific for reading the bands of the precipitation. Results: The sample comprised 47 individuals: 22 smokers who smoked 30 cigarettes or more per day for more than 10 years, and 25 non-smokers, who composed the control group. The Mann- Whitney test (P<0.05) found no significant difference between the groups with regard to either the concentration of the SIgA or the salivary flow. The median value of the salivary flow was 0.73 among the smokers and 0.70 among the non-smokers, and the median for SIgA was 10.20 among the nonsmokers and 7.93 among the smokers. Conclusion: There were no significant differences in the levels of SIgA and salivary flow between the smokers and the non-smokers in the investigated sample.References
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