Evaluation of organic and inorganic compounds in the saliva of patients with chronic periodontal disease

  • Arnaud Alves Bezerra Jr Universidade de Taubaté - UNITAU
  • Débora Pallos Universidade de Taubaté - UNITAU
  • José Roberto Cortelli Universidade de Taubaté - UNITAU
  • Cintia Helena Cury Saraceni Universidade Paulista - UNIP
  • Celso Silva Queiroz Universidade Paulista - UNIP
Keywords: Dental plaque, periodontitis, saliva, alkaline phosphatase, urea

Abstract

Purpose: The aim of this study was to evaluate the influence of periodontal disease on the biochemical parameters of the saliva, including salivary flow rate, pH, total protein, alkaline phosphatase activity and urea concentration, in individuals with chronic periodontitis. Methods: Forty subjects were allocated into two groups: twenty subjects without periodontal disease (control group) and twenty subjects with chronic periodontitis (test group). Plaque index (PI), gingival index (GI), probing depth (PD) and clinical attachment level (CAL) were obtained by a previously trained and calibrated clinical examiner. Saliva from both groups was collected for analysis of its biochemical parameters. The Student’s t-test and correlation coefficient (Pearson) were used at a 5% level of significance. Results: The results showed alterations in the alkaline phosphatase activity, urea concentration and total protein in the subjects of the test group compared to the control group (P < 0.05). However, there was no correlation between the clinical periodontal parameters and the salivary parameters (P > 0.05). Conclusion: The results suggest that chronic periodontitis can affect the composition of the saliva and that analysis of the salivary parameters can be useful as an additional exam for the diagnosis of periodontal disease.

Author Biographies

Arnaud Alves Bezerra Jr, Universidade de Taubaté - UNITAU
Research Fellowship, Department of Dentistry, University of Taubaté, Taubaté, SP, Brazil
Débora Pallos, Universidade de Taubaté - UNITAU
Department of Dentistry, University of Taubaté, Taubaté, SP, Brazil
José Roberto Cortelli, Universidade de Taubaté - UNITAU
Department of Dentistry, University of Taubaté, Taubaté, SP, Brazil
Cintia Helena Cury Saraceni, Universidade Paulista - UNIP
Professora doutorada - Department of Dentistry, Paulista University, São Paulo, SP, Brazil
Celso Silva Queiroz, Universidade Paulista - UNIP
Departamento de Odontologia Área de Cariologia - Department of Dentistry, Paulista University, São Paulo, SP, Brazil
Published
2010-06-30
Section
Original Article