Effect of lincomycin treatment of root surface in dental replantation: A study in rats

  • Daniela Nascimento Silva PUCRS
  • Wâneza Dias Borges PUCRS
  • Beatriz Farias Vogt PUCRS
  • Aline Adelaide Paz da Silva Duarte PUCRS
  • José de Amorim Lisboa-Neto Universidade Federal de Alagoas - UFAL
  • Stela Maris Wanderley Nobre Universidade Federal de Alagoas - UFAL
Keywords: Replantation, lincomycin, dental trauma

Abstract

Purpose: The purpose of studies on antibiotics used topically on the root surface of avulsed teeth is to evaluate their antiresorptive properties which favor the repair of the periodontal ligament and the reestablishment of the dentoalveolar articulation. The aim of the present study was to determine the effect of lincomycin treatment of the root surface on tooth replantation. Methods: Ten rats were distributed into two groups (I – control; II – experimental). The right maxillary incisor of the animals was extracted and stored in milk for 30 min. The tooth in group I was rinsed with normal saline and replanted; in group II, the incisor was immersed in lincomycin for 5 min before replantation. The animals were euthanized on the 21st day postoperative. The right hemimaxilla was submitted to histological sectioning and stained with H&E for microscopic evaluation. Results: Group I: the periodontal ligament appeared dispersed, with moderate to intense lymphoplasmacytic infiltrate, and dentoalveolar articulation was not reestablished. Group II: complete repair of the ligament was evident, and there were few inflammatory cells and small areas of inflammatory resorption and ankylosis. Conclusion: The use of lincomycin allowed the repair of the periodontal ligament and reduced inflammation. There were still areas of inflammatory resorption and ankylosis.

Author Biographies

Daniela Nascimento Silva, PUCRS
Departamento de Cirurgia Área - Cirurgia e Traumatologia Bucomaxilofacial
Wâneza Dias Borges, PUCRS
Bolsista CNPq. Mestranda em Odontologia, área de concentração Cirurgia e Traumatologia Bucomaxilofacial - PUCRS.
Beatriz Farias Vogt, PUCRS
Bolsista CNPq. Mestranda em Odontologia, área de concentração Cirurgia e Traumatologia Bucomaxilofacial - PUCRS.
Aline Adelaide Paz da Silva Duarte, PUCRS
Acadêmica do Curso de Graduação em Odontologia da PUCRS
José de Amorim Lisboa-Neto, Universidade Federal de Alagoas - UFAL
Professor do Departamento de Odontologia da Universidade Federal de Alagoas.
Stela Maris Wanderley Nobre, Universidade Federal de Alagoas - UFAL
Professora do Departamento de Odontologia da Universidade Federal de Alagoas.
Published
2009-04-10
Section
Original Article