Ossifying fibroma – diagnosis, treatment, and follow-up: case report and literature review

  • Fernando de Oliveira Andriola Pontifícia Universidade Católica do Rio Grande do Sul
  • Leonardo Matos Santolim Zanettini Pontifícia Universidade Católica do Rio Grande do Sul
  • Bernardo Ottoni Braga Barreiro Pontifícia Universidade Católica do Rio Grande do Sul
  • Valéria Rodrigues Saraiva Pontifícia Universidade Católica do Rio Grande do Sul
  • Fábio Luiz Dal Moro Maito Pontifícia Universidade Católica do Rio Grande do Sul
  • Guilherme Genehr Fritscher Pontifícia Universidade Católica do Rio Grande do Sul
  • Cláiton Heitz Pontifícia Universidade Católica do Rio Grande do Sul
  • Rogério Miranda Pagnoncelli Pontifícia Universidade Católica do Rio Grande do Sul
Keywords: Surgery, Oral, Pathology, Fibroma, Ossifying


OBJECTIVE: This article presents a case of ossifying fibroma (OF), including its diagnosis, treatment, and 15-month clinical and radiographic follow-up as well as a review of the literature about this pathology.
CASE REPORT: A routine panoramic radiograph of a 27-year-old, systemically healthy, white woman revealed a radiolucent lesion with well-defined sclerotic margins of approximately 3 × 2 cm in the mandible. The histopathological diagnosis revealed it was an OF. Lower Right Canine and Lower Right First Premolar teeth were endodontically treated for later surgical removal of the tumor. There was no history of trauma in the region.
CONCLUSION: OF is a benign fibro-osseous tumor of the craniofacial bones commonly involving the jaws, especially the mandible. The diagnosis is based on a combination of clinical, radiographic and histologic criteria. Conservative treatment is an effective option that reduces morbidity and simplifies postoperative rehabilitation. We emphasize the importance of properly documenting individual cases and interpreting postoperative radiographic images along with the patients in order to avoid possible confusion between areas of bone repair and of potentially suspicious lesions in the future.


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Case Report