Susceptibility of anaerobic bacteria isolated from periimplantar and periodontal infections to metronidazole, lincosamines, macrolides and tetracyclines

Authors

  • Elerson Gaetti-Jardim Jr
  • Ellen Cristina Gaetti-Jardim
  • Samira Âmbar Lins
  • Sergio Ricardo Oliveira
  • Alex Semenoff Segundo

Keywords:

microbiology, periodontology, antimicrobials

Abstract

The goal of this study was to evaluate the susceptibility of microorganims isolated from periimplantar and periodontal infections to metronidazole, lincosamides, tetracycline and macrolides. The tested drugs were azithromycin, clarithromycin, erythromycin, clindamycin, lincomycin, metronidazole and tetracycline. The tests were carried out by mean an agar dilution method, and the culture medium employed was Wilkins-Chalgren agar. 187 strict and facultative anaerobic isolates were submitted to the susceptibility tests. The bacterial inoculum was standardized to 105 cells/spot, which were transferred to the agar medium by means of a Steers’ replicator (Cefar Ltd, São Paulo, Brazil). The results showed a significant resistance to erythromycin; lincomycin and tetracycline, while clindamycin, metronidazole, and the newer macrolides showed a higher antimicrobial activity.
UNITERMS: microbiology; periodontology; antimicrobials.

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Published

2007-07-03

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Section

Original Article