Effectiveness of Acmella oleracea for topical anesthesia on buccal mucosa
AbstractObjective: The present study aimed to determine the effectiveness and safety of Acmella oleracea ointment used as topical anesthetic for buccal mucosa. Methods: The topical agent was applied to dried buccal mucosa. Next, a short needle was inserted in the mucobuccal fold above the maxillary canine eminence and then immediately removed. Each volunteer served as his/her own control. Pain was measured with a visual analogue scale and by heart rate. Results: A one-way analysis of variance followed by a Kruskal-Wallis test showed no statistically significant differences in the effectiveness of the two Acmella oleracea ointment concentrations studied compared to the benzocaine 20% (P<0.05) control. Conclusion: Acmella oleracea ointment was effective and safe in reducing the pain from needle insertion in the methodology used in the present study.
Ojugas AC. A dor através da história e da arte. Cleveland: Atlas Medical Publishing; 1999.
Mersky YH. Classification of chronic pain. Descriptions of chronic pain syndromes and definitions of pain terms. Prepared by the International Association for the Study of Pain, Subcommittee on Taxonomy. Pain Suppl 1986; 3:S1-S226.
Malamed SF. Manual de Anestesia Local. 5. ed. Rio de Janeiro: Elsevier; 2005.
Lorenzi H, Matos FJA. Plantas medicinais no Brasil: nativas e exóticas. Nova Odessa: Instituto Plantarum; 2002.
Prachayasittikul S, Suphapong S, Worachartcheewan A, Lawung R,
Ruchirawat S, Prachayasittikul V. Bioactive Metabolites from Spilanthes acmella Murr. Molecules 2009;14:850-67.
Rosivack RG, Koenisberg SR, Maxwell KC. An analysis of the effectiveness of two topical anesthetics. Anesth Prog 1990;37:290-2.
Ramos-e-Silva M, Ferreira AF, Bibas R, Carneiro S. Clinical Evaluation of fluid extract of chamomilla recutita for oral aphtae. J Drugs Dermatol 2006;5:612-7.
Bergius M, Kiliaridis S, Berggren U. Pain in orthodontics. A review and discussion of the literature. J Orofac Orthop 2000;61:125-37.
Vulpi TS, Morais COM, Trindade APF, Lima MCHP, Velozo LSM, Kaplan MAC. Análise do óleo essencial dos diferentes órgãos de Acmella ciliata Kunth (Asteraceae). Rev Bras Bioc 2007;5:1128-30.
Farmacopéia Brasileira. 4. ed. São Paulo: Atheneu; 1988.
Martin MD, Ramsay D, Whitney C, Fiset L, Weinstein P. Topical anesthesia: differentiating the pharmacological and psychological contributions to efficacy. Anesth Prog 1994;41:40-7.
Kincheloe JE, Mealiea WL Jr, Mattison GD, Seib K. Psychophysical
measurement on pain perception after administration of a topical
anesthetic. Quintessence Int 1991;22:311-5.
Boleta-Ceranto DCF, Bianchi FJ, Miura CSN, Veiga MCFA, Bremm LL. Influence of orofacial pain, in superficial and deep tissue, on the anxiety levels in rats. Rev Odonto Ciênc 2010;25:376-81.
Fischer L, Torres-Chávez KE, Clemente-Napimoga JT, Jorge D, Arsati F, de Arruda Veiga MC, Tambeli CH. The influence of sex and ovarian hormones on temporomandibular joint nociception in rats. J Pain 2008; 9:630-8.
Popescu A, LeResche L, Truelove EL, Drangsholt MT. Gender differences in pain modulation by diffuse noxious inhibitory controls: a systematic review. Pain 2010;150:309-18.
Nusstein JM, Beck M. Effectiveness of 20% benzocaine as a topical
anesthetic for intraoral injections. Anesth Prog 2003;50:159-63.
Hersh EV, Houpt MI, Cooper SA, Feldman RS, Wolff MS, Levin LM.
Analgesic efficacy and safety of an intraoral lidocaine patch. JADA
Nakanishi O, Haas D, Ishikawa T, Kameyama S, Nishi M. Efficacy of
mandibular topical anesthesia varies with the site of administration. Anesth Prog 1996;43:14-9.
Meechan JG, Gowans A, Welbury R. The use of patient controlled
transcutaneous electronic nerve stimulation (TENS) to decrease the discomfort of regional anesthesia in dentistry: a randomized controlled clinical trial. J Dent. 1998;26:417-20
Rosa AL, Sverzut CE, Xavier SP, Lavrador MA. Clinical effectiveness of lidocaine and benzocaine for topical anesthesia. Anesth Prog 1999;46:97-9.
Donaldson D, Meechan JG. A comparison of the effects of EMLA cream and topical 5% lidocaine on discomfort during gingival probing. Anesth Prog. 1995;42:7-10.
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