Histological analysis of experimental wound healing under the action of low power laser [Abstract in English]<\b>

Jesus Antonio de Carvalho Abreu, Aline da Luz Sousa, Carmen Laís Gervásio Fônseca Alves, Jefferson Torres Nunes


Aims: To assess histologically the healing of experimental skin wounds in Rattus norvergicus using low-power laser.
Methods: Forty-five males were divided into three groups according to the adopted therapy (untreated, treated with laser at a dose of 4 J/cm2 and treated with laser at a dose of 8 J/cm2), which were divided into three subgroups according to time of euthanasia (7, 14 and 21 days). A fragment of 2 cm in diameter of skin was removed from the back of each animal, and laser was irradiated every 24 hours in the fragments of the treated groups, with the previously established dose.
Results: At seven days after the experiment, the low-power laser irradiated groups showed a more efficient reepithelialization when compared with the untreated group. Furthermore, the groups treated with laser showed a more marked deposition of collagen at 14 days. Dose adjusted in 4 J/cm2 was more effective.
Conclusions: Low-power laser has enhanced the healing of experimental skin wounds in Rattus norvergicus. The adjusted dose in 4 J/cm2 was more effective.



This journal is a member of COPE (Committee on Publication Ethics) and follow the principles recommended by this international reference organization on integrity and ethics in scientific publication.

Licença Creative Commons
Except where otherwise noted, the material published in this journal is licensed under a Creative Commons Attribution 4.0 International licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original publication is properly cited.
Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

 Member of OASPA

Copyright: © 2006-2019 EDIPUCRS