Identification of cardiovascular risk by triglyceride/HDL- cholesterol ratio in patients with chronic renal disease in hemodialysis

Luciana Leitão Moraes, Alinne Lorrany Gomes dos Santos, Luciana Pereira Pinto Dias, Dyanara de Almeida Oliveira, Denise Mafra, Isabelle Christine Vieira da Silva Martins

Abstract


***Identification of cardiovascular risk by triglyceride/HDL- cholesterol ratio in patients with chronic renal disease in hemodialysis***

AIMS: To identify cardiovascular risk by triglyceride/high density lipoprotein cholesterol ratio (TG/HDL-c) and to verify its association with socio-demographic factors, clinical parameters and body mass index in patients with chronic renal disease on hemodialysis.

METHODS: Cross-sectional study, in which patients with chronic kidney disease in hemodialysis were evaluated. A non-probability convenience sampling was used. Sociodemographic data were collected through a semi-structured questionnaire interview, and clinical and laboratory data were obtained from the medical records. For the identification of cardiovascular risk, the TG/HDL-c ratio was calculated from plasma triglycerides (mg/dL) and high density lipoprotein cholesterol (mg/dL). The cut-off point for TG/HDL-c considered to be indicative of cardiovascular risk was ≥3.8 mg/dL. For statistical analysis, the chi-square test was used, and the significance level was set at 5% (p <0.05).

RESULTS: A total of 71 patients were evaluated, with a mean age of 49.9±13.2 years, being 28 women (50.1±13.2 years) and 43 men (49.7±13.2 years). Among the 71 patients, 31 (43.66%) had cardiovascular risk characterized by the TG/HDL-c ratio ≥3.8 mg/dL. In general, the profile of patients with and without cardiovascular risk was similar. However, in patients with cardiovascular risk there was a higher proportion of males (77.42%), while in those who did not have this risk, the female gender was more frequent (52.50%). This variable showed a significant difference between the groups with and without cardiovascular risk (p=0.011).

CONCLUSIONS: In this sample of patients with chronic kidney disease on hemodialysis, the TG/HDL-c ratio identified a high cardiovascular risk index, which was significantly associated with males.


Keywords


chronic renal disease; cardiovascular diseases; risk factors; hemodialysis.

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DOI: http://dx.doi.org/10.15448/1980-6108.2017.3.27369

 

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