Antimicrobial activity of 2% chlorhexidine gluconate, 1% sodium hypochlorite and paramonochlorophenol combined with furacin against S. aureus, C. albicans, E. faecalise and P. aureginosa

Tereza A. Delle Vedove Semenoff, Alex Semenoff-Segundo, Alvaro Henrique Borges, Fabio Miranda luiz Pedro, Leonardo Stephan Caporossi, Aurélio Rosa-Júnior


Purpose: To analyze the antimicrobial action of 2% chlorhexidine gluconate, 1% sodium hypochlorite and paramonochlorophenol were combined with furacin against strains of S. aureus, C. albicans, E. faecalis and P. aureginosa.
Methods: Forty Petri plates were used. Four plates were separated from the others and used as a negative control. Four other plates were used a positive control. The other 32 plates were treated with four circles of sterilized filter paper impregnated with the test and control substances. The groups of plates were analyzed after an experiment time of seven days by the measuring the inhibition halos.
Results: Two percent chlorhexidine gave the largest inhibition zones, and the difference in size between its inhibition zones and the compound with the next largest inhibition zone, 1% sodium hypochlorite, was statistically significant. The 1% sodium hypochlorite also had significantly larger inhibition zones than the control group and PMC+F.
Conclusion: Two percent chlorhexidine gluconate gave the best results, while PMC+F showed the weakest antibacterial activity.


Chlorhexidine; sodium hypochlorite; Endodontics

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e-ISSN: 1980-6523

ISSN-L: 0102-9460


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