Canalicular adenoma of the upper lip: A case report

Authors

  • Marion Farias Guimarães Universidade Federal do Amazonas
  • Nikeila Chacon de Oliveira Conde Universidade Federal do Amazonas
  • Juliana Vianna Pereira Universidade Federal do Amazonas
  • Max Eduardo Barroso Amorim Universidade Federal do Amazonas
  • Suzana Cantanhede Orsini Machado de Sousa Universidade de São Paulo
  • Tatiana Nayara Libório-Kimura Universidade Federal do Amazonas

DOI:

https://doi.org/10.15448/1980-6523.2015.4.19549

Keywords:

Adenoma, Diagnosis, differential, Salivary glands, Immunohistochemistry

Abstract

Objective: Canalicular adenoma is a relatively rare benign tumor of the salivary glands, found almost exclusively in the minor salivary glands of the upper lip. We report a case of canalicular adenoma in the upper labial mucosa of a male patient, highlighting the clinical and histopathological differential peculiarities compared to other lesions of similar location. The immunohistochemistry was considered decisive for diagnosis confirmation and differentiation from lesions that may have similar histological characteristics.

Case Description: A 68-year-old melanoderm male patient sought dental care for an asymptomatic lesion in the upper lip, measuring 7 mm, with 1 year of evolution. Excisional biopsy, microscopic evaluation, and immunohistochemical assays were performed using antibodies against CK7,
S-100, and vimentin antigens. The final diagnosis of canalicular adenoma was established through the consolidation of clinical, histological, and immunohistochemical data, taking into account the differential diagnosis of this lesion. After 1 year, the patient had no recurrences.

Conclusion: Immunohistochemistry was a definitive tool for the final diagnosis, ruling out the possibility of other lesions with similar morphology.

Author Biographies

Marion Farias Guimarães, Universidade Federal do Amazonas

Cirurgiã-Dentista. Faculdade de Odontologia da Universidade Federal do Amazonas, Manaus-AM, Brasil

Nikeila Chacon de Oliveira Conde, Universidade Federal do Amazonas

Doutora em Odontologia pela Universidade Federal da Paraíba, professora adjunta da Universidade Federal do Amazonas, Manaus-AM, Brasil.

Juliana Vianna Pereira, Universidade Federal do Amazonas

Doutora em Biotecnologia pela Universidade Federal do Amazonas, professora adjunta da Universidade Federal do Amazonas, Manaus-AM, Brasil.

Max Eduardo Barroso Amorim, Universidade Federal do Amazonas

Especialista em Cirurgia e Traumatologia Buco-Maxilo-Facial pela Associação Brasileira de Odontologia, professor assistente da Universidade Federal do Amazonas, Manaus-AM, Brasil.

Suzana Cantanhede Orsini Machado de Sousa, Universidade de São Paulo

Doutora em Anatomia Patológica e Patologia Clínica pela National Institutes of Health, professora titular da Universidade de São Paulo, São Paulo-SP, Brasil.

Tatiana Nayara Libório-Kimura, Universidade Federal do Amazonas

Doutora em Patologia Bucal pela Universidade de São Paulo, professora adjunta da Universidade Federal do Amazonas, Manaus-AM, Brasil.

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Published

2016-03-21

Issue

Vol. 30 No. 4 (2015)

Section

Case Report

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