Oral manifestations in chronic kidney failure patients

Authors

  • Renata Cristina Canuto Reis Positivo University
  • João Armando Brancher Positivo University
  • Tatiana Miranda Deliberador Positivo University
  • Ana Tereza Bittencourt Guimarães Universidade do Oeste do Paraná
  • Allan Fernando Giovanini Positivo University
  • João Cézar Zielak Positivo University.

DOI:

https://doi.org/10.15448/1980-6523.2016.1.19521

Keywords:

Hemodialysis, Chronic kidney failure, Oral health

Abstract

Objective: Chronic kidney failure (CKF) is a progressive deterioration of the kidneys. The goal of this study was to analyze the oral manifestation of CKF in a sample of hemodialysis and transplanted patients.
Methods: Eighty-three records of patients treated in the Pro-Renal Foundation in Curitiba, Brazil were used. The records were separated in four groups: Transplanted Men (TM = 14), Transplanted Women (TW = 18), Men in Hemodialysis (MHD = 28) and Women in Hemodialysis (WHD = 23). Information about oral and systemic health condition were collected. Data from each group were submitted to correspondence analysis and quantitative variables were compared by Kruskal-Wallis
and Dunn’s test. Significance level was 0.05.
Results: Gingival inflammation, loss of periodontal support tissue, dental calculus and increase in periodontal probing depth were common findings in all patients, but significant association was found in following groups: TM presented dental calculus; TW presented a high prevalence of cardiovascular problems and saburral tongue; MHD presented poor oral hygiene, gingivitis associated with smoking; WHD presented a high prevalence of temporomandibular dysfunction.
Conclusions: The most prevalent findings were increase in the periodontal probing depth and gingival recession. Unexpectedly, WHD group presented a high prevalence of temporomandibular dysfunction.

Author Biographies

Renata Cristina Canuto Reis, Positivo University

Master’s Program in Clinical Dentistry,

João Armando Brancher, Positivo University

Master’s Program in Clinical Dentistry

Tatiana Miranda Deliberador, Positivo University

Master’s Program in Clinical Dentistry

Ana Tereza Bittencourt Guimarães, Universidade do Oeste do Paraná

Department of Statistics

Allan Fernando Giovanini, Positivo University

Master’s Program in Clinical Dentistry

João Cézar Zielak, Positivo University.

Master’s Program in Clinical Dentistry

References

Stenvinkel P, Carrero JJ, Axelsson J, Lindholm B, Heimburger O, Massy Z. Emerging biomarkers for evaluating cardiovascular risk in the chronic kidney disease patient: How do new pieces fit into the uremic puzzle? Clin J Am Soc Nephrol. 2008;3:505–21.

Chan JC, Williams DM, Roth KS. Kidney failure in infants and children. Pediatr Rev. 2002;23:47-60.

Censo da SBN Jan/2011. Available at: http://www.sbn.org.br. Accessed may 26, 2012.

Proctor R, Kumar N, Stein A, Moles D, Porter S. Oral and dental aspects of chronic renal failure. J Dent Res. 2005;84:199-208.

Bokor-Bratic M. Clinical significance of analysis of immunoglobulin A levels in saliva. Med Pregl. 2000;53:164-68.

López-Pintor RM, Hernández G, de Arriba L, Morales JM, Jiménez C, de Andrés A. Oral ulcers during the course of cytomegalovirus infection in renal transplant recipients. Transplant Proc. 2009;41(6):2419-21.

Carrero JJ, Stenvinkel P. Persistent Inflammation as a Catalyst for Other Risk Factors in Chronic Kidney Disease: A Hypothesis Proposal. Clin J Am Soc Nephrol. 2009;4:49-55.

Souza CM, Braosi AP, Luczyszyn SM, Casagrande RW, Pecoits-Filho R, Riella MC, Ignacio SA, Trevilatto PC. Oral health in Brazilian patients with chronic renal disease. Rev Med Chil. 2008;136:741-6.

Hata T, Irei I, Tanaka K, Nagatsuka H, Hosoda M: Macrognathia secondary to dialysis-related renal osteodystrophy treated successfully by parathyroidectomy. Int J Oral Maxillofac Surg. 2006;35:378-82.

Jacek Borawski, Magdalena Wilczynska-Borowska, Wanda Stokowska, Michał Mysliwiec. The periodontal status of pre-dialysis chronic kidney disease and maintenance dialysis patients. Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association. European Renal Association. 2007;22(2):457-64.

Vaziri ND. Dyslipidemia of chronic renal failure: the nature, mechanisms, and potential consequences. Am J Physiol Renal Physiol. 2006;290: 262-72.

Watanabe S, Noboru M, Yasunari M, Ideura T. A Cross-Sectional Study on the Effects of Long Term Very Low Protein Diets in Patients with Chronic Kidney Disease - Serum and Urine DEXA and Amino Acid Profiles. Anti-aging Med. 2010;7(2):7-13.

Levin A, Djurdjev O, Barrett B, Burgess E, Carlisle E, Ethier J, Jindal K, Mendelssohn D, Tobe S, Singer J, Thompson C. Cardiovascular disease in patients with chronic kidney disease: Getting to the heart of the matter. Am J Kidney Dis. 2001;38(6):1398-407.

Bayraktar G, Kurtulus I, Kazancioglu R, Bayramgurler I, Cintan S, Bural C, Bozfakioglu S, Issever H, Yildiz A. Oral health and inflammation in patients with end-stage renal failure. Perit Dial Int. 2009;29(4):472-9.

Marakoglu I, Gursoy UK, Demirer S, Sezer H. Periodontal Status of Chronic Renal Failure Patients Receiving Hemodialysis. Yonsei Med J. 2003;44(4):648-652.

Thorman R, Neovius M, Hylander B. Scand J Prevalence and early detection of oral fungal infection: a cross-sectional controlled study in a group of Swedish end-stage renal disease patients. Urol Nephrol. 2009;43(4):325-30.

Craig RG, Spittle MA, Levin NW. Importance of periodontal disease in the kidney patient. Blood Purif. 2002;20(1):113-9.

Kshirsagar AV, Craig RG, Beck JD, Moss K, Offenbacher S, Kotanko P, Yoshino M, Levin NW, Yip JK, Almas K, Lupovici E, Falk RJ: Severe periodontitis is associated with low serum albumin among patients on maintenance hemodialysis therapy. Clin J Am Soc Nephrol. 2007;2: 239-44.

Borawski J, Wilczynska-Borawska M, Stokowska W, Mysliwiec M: The periodontal status of pre-dialysis chronic kidney disease and maintenance dialysis patients. Nephrol Dial Transplant. 2007;22:457-64.

Kho HS, Lee SW, Chung SC, Kim YK. Oral manifestations and salivary flow rate, pH, and buffer capacity in patients with endstage renal disease undergoing hemodialysis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88:316-9.

Martins C, Siqueira WL, Primo LSSG. Oral and salivary flow characteristics of a group of Brazilian children and adolescents with chronic renal failure. Pediatr Nephrol. 2008;23:619-24.

Hruska K. New concepts in renal osteodystrophy. Nephrol Dial Transplant. 1998;13:2755-60. 23. Kalyvas D, Tosios KI, Leventis MD, Tsiklakis K, Angelopoulos AP. Localized jaw enlargement in renal osteodystrophy: report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004;97:68-74.

Bots CP, Poorterman JH, Brand HS, Kalsbeek H, van Amerongen BM, Veerman EC, Nieuw Amerongen AV. The oral health status of dentate patients with chronic renal failure undergoing dialysis therapy. Oral Dis. 2006;12(2):176-80.

Yamamoto S, Kazama JJ, Narita I, Naiki H, Gejyo F. Recent progress in understanding dialysis-related amyloidosis. Bone. 2009;45(1):39-42.

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Published

2016-11-17

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