Clinicopathological, histochemical and immunohistochemical aspects of angioleiomyoma of the cheek: a case report

Paula Daniele Matheus, Manoela Domingues Martins, Luise Meurer, Lucas N. Sant´Ana, Manoel Santa’Ana Filho


Introduction: Leiomyomas are benign smooth muscle neoplasms that preferably affect the genitals, skin, and gastrointestinal tract, being rarely seen in the oral cavity. They  re commonly classified into three microscopic patterns: solid leiomyoma, angioleiomyoma (ALM), and epithelioid leiomyoma. The most frequently reported sites of occurrence of oral ALM are the lip (48.6%), palate (21.1%), buccal mucosa and tongue (9.2%), and intraosseous lesions (8.3%).
Case report: A 62 years old male presented a painless swelling in the left cheek. In this report histopathological and immunohistochemical analysis were made to confirm the diagnosis, since several lesions were possible. The treatment was local surgical excision of the tumor.


angioleiomyoma, smooth muscle neoplasms, benign neoplasm, oral lesions.

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