Effectiveness of Acmella oleracea for topical anesthesia on buccal mucosa

Lucas Cerutti de Andrade, Isabella Welter Rotta, Sandro Revay Chaves, Denise Tiemi Uchida, Zilda Cristiani Gazim, Fabiana Borges Padilha Ferreira, Ezilda Jacomassi, Daniela de Cassia Faglioni Boleta-Ceranto

Abstract


Objective: The present study aimed to determine the effectiveness and safety of Acmella oleracea ointment used as topical anesthetic for buccal mucosa.
Methods: The topical agent was applied to dried buccal mucosa. Next, a short needle was inserted in the mucobuccal fold above the maxillary canine eminence and then immediately removed. Each
volunteer served as his/her own control. Pain was measured with a visual analogue scale and by heart rate.
Results: A one-way analysis of variance followed by a Kruskal-Wallis test showed no statistically significant differences in the effectiveness of the two Acmella oleracea ointment concentrations studied compared to the benzocaine 20% (P<0.05) control.
Conclusion: Acmella oleracea ointment was effective and safe in reducing the pain from needle insertion in the methodology used in the present study.

Keywords


Acmella oleracea; benzocaine; pain; topical anesthetic;

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