Weight evolution during the first year of renal transplantation and the occurrence of Diabetes Mellitus after 5 years of follow-up
DOI:
https://doi.org/10.15448/1983-652X.2014.3.19754Keywords:
renal transplantation, weight gain, nutritional status, nutritional and metabolic diseasesAbstract
Introduction: The late post-transplant period is characterizes by a series of nutritional changes, which can reduce organ and patient survival.
Objective: To evaluate the evolution of patient’s weight during the first year after renal transplantation (RT) and the occurrence of diabetes mellitus (DM) after 5 years of follow-up.
Materials and Methods: A retrospective cohort study was performed. Weight and other clinical data were collected in the records of the Department of Nephrology, São Lucas University Hospital of PUCRS in Porto Alegre.
Results: 35 patients were studied. At the end of the first year (data classified as T12), we observed an average weight gain of 8.2%, while 29 (82.9%) gained weight. The increase becomes significant from sixth month (T6) to ninth month (T9) in women and in men. The weight gain promotes impact on BMI, with significant difference between the beginning (T0) (23.2 ± 4.3kg/m2) and the end of the first year after RT (T12) (24.9 ± 4.4 kg/m2) (p<0.001). At the end of the fifth year, there were 6 deaths (17.1%) and 2 (5.7%) graft losses. Of the 27 patients, there was a 18.5% incidence of DM, which showed higher weight gain, although not statistically different, and an increase during the first year of RT (13.6% of usual weight) higher in comparison with the group that did not develop this condition (4.7% of the usual weight).
Conclusions: There was an increase in weight after one year of RT, and the patients who developed DM after 5 years of follow-up showed a different weight gain profile, although data were not significant.
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